酸酐诱导的2-(1-羟基-1-苯烷基)苯酚一步合成邻酰氧基二芳基烯烃

doi:10.6023/cjoc201807024

有机化学 ›› 2019, Vol. 39 ›› Issue (2): 532-537.DOI: 10.6023/cjoc201807024 上一篇下一篇

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酸酐诱导的2-(1-羟基-1-苯烷基)苯酚一步合成邻酰氧基二芳基烯烃

吕雯雯^a, 贺信淳^a, 施敏^a,b, 王飞军^a

a 华东理工大学化学与分子工程学院上海 200237;
b 中国科学院上海有机化学研究所金属有机化学国家重点实验室上海 200032

收稿日期:2018-07-16 修回日期:2018-09-04 发布日期:2018-09-26
通讯作者: 王飞军 E-mail:feijunwang@ecust.edu.cn
基金资助:
国家自然科学基金（No.21372075）和上海浦江人才计划（No.16PJD017）资助项目.

Anhydride Induced One-Pot Synthesis of ortho-Acyloxy Diarylalkenes from 2-(1-Hydroxy-1-arylalkyl)phenols

Lü Wenwena^a, He Xinchuna^a, Shi Mina^a,b, Wang Feijun^a

a School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237;
b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Received:2018-07-16 Revised:2018-09-04 Published:2018-09-26
Contact: 10.6023/cjoc201807024 E-mail:feijunwang@ecust.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21372075) and the Shanghai Pujiang Program (No. 16PJD017).

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1. 酸酐诱导的2-(1-羟基-1-苯烷基)苯酚一步合成邻酰氧基二芳基烯烃.PDF(5370KB)

摘要/Abstract

报道了2-（1-羟基-1-苯烷基）苯酚与酸酐和三乙胺的反应，为合成邻酰氧基二芳基烯烃提供了一种切实可行的方法，它是许多生物活性物质的重要组成和很多有机合成的起始原料.该反应可以在一步中实现，在温和的条件下具有优异的产率.

关键词: 2-(1-羟基-1-苯乙基改为苯烷基)苯酚, 邻酰氧基二芳基烯烃, 温和的条件, 酸酐促进的反应

Reaction of 2-(1-hydroxy-1-arylalkyl)phenols with anhydride and NEt₃ was reported, providing a practical way to the synthesis of ortho-acyloxy diarylalkenes, which is an important motif in many bioactive compounds and starting materials in many organic synthesis. This reaction can be achieved in one pot reaction under mild conditions in good yields.

Key words: 2-(1-hydroxy-1-arylalkyl)phenols, ortho-acyloxy diarylalkenes, mild conditions, anhydride promoted reaction

引用此文

吕雯雯, 贺信淳, 施敏, 王飞军. 酸酐诱导的2-(1-羟基-1-苯烷基)苯酚一步合成邻酰氧基二芳基烯烃[J]. 有机化学, 2019, 39(2): 532-537.

Lü Wenwena, He Xinchuna, Shi Mina, Wang Feijun. Anhydride Induced One-Pot Synthesis of ortho-Acyloxy Diarylalkenes from 2-(1-Hydroxy-1-arylalkyl)phenols[J]. Chin. J. Org. Chem., 2019, 39(2): 532-537.

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酸酐诱导的2-(1-羟基-1-苯烷基)苯酚一步合成邻酰氧基二芳基烯烃

Anhydride Induced One-Pot Synthesis of ortho-Acyloxy Diarylalkenes from 2-(1-Hydroxy-1-arylalkyl)phenols

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