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2012 , Vol. 32 >Issue 05: 815 - 824

DOI: https://doi.org/10.6023/cjoc1202021

综述与进展

从三氟甲基化反应的近年进展看有机氟化学的发展趋势

  • 卿凤翎
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  • a 中国科学院上海有机化学研究所有机氟化学重点实验室，上海200032;
    b 东华大学化学化工与生物工程学院，上海201620

收稿日期: 2012-02-02

  修回日期: 2012-03-01

  网络出版日期: 2012-04-10

基金资助

国家自然科学基金(Nos. 21072028, 20832008)和国家重点基础研究发展计划(No. 2012CB21600)资助项目.

收起

Recent Advances of Trifluoromethylation

  • Qing Feng-Ling
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  • a Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032;
    b College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620

Received date: 2012-02-02

  Revised date: 2012-03-01

  Online published: 2012-04-10

Supported by

Project supported by the National Natural Science Foundation of China (Nos. 21072028, 20832008) and the National Basic Research Program of China (No. 2012CB21600).

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摘要

由于含三氟甲基的化合物在医药、农药等领域得到广泛应用, 发展向有机分子引入三氟甲基的方法成为当前的热点研究课题. 分别总结了国外和我国学者近年(主要是2009～2011 年)在三氟甲基化反应研究领域取得的研究成果.从近年三氟甲基化反应的研究进展, 作者提出一些值得关注的有机氟化学发展方向.

关键词： 三氟甲基化; 有机氟化学; 进展

本文引用格式

卿凤翎 . 从三氟甲基化反应的近年进展看有机氟化学的发展趋势[J]. 有机化学, 2012 , 32(05) : 815 -824 . DOI: 10.6023/cjoc1202021

Abstract

Many biologically active compounds contain the CF3 groups as the essential motif. As a result, much attention has been paid to the development of new synthetic methods for the introduction of the CF3 groups into diverse organic compounds. This review takes a critical look at recent advances of trifluoromethyltion reactions.

Key words： trifluoromethylation; organofluorine chemistry; advance

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