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2012 , Vol. 32 >Issue 06: 1112 - 1115

DOI: https://doi.org/10.6023/cjoc1202054

研究简报

微波辐射下一步合成4-芳基-2,6-二(3,3'-香豆素基)吡啶衍生物

  • 周建峰 ,
  • 娄风文 ,
  • 孙小军 ,
  • 安礼涛 ,
  • 支三军 ,
  • 霍娟娟 ,
  • 郑丽 ,
  • 王星帅
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  • 淮阴师范学院化学化工学院, 江苏省低维材料化学重点建设实验室, 淮安 223300

收稿日期: 2012-02-05

  修回日期: 2012-03-22

  网络出版日期: 2012-04-10

基金资助

江苏省低维材料化学重点建设实验室开放基金(JSKC11101)资助项目.

收起

One-Pot Synthesis of 3,3'-(4-arylpyridine-2,6-diyl)-bis (2H-chromen-2-one) Derviatives under Microwave Irradiation

  • Zhou ,
  • Jianfeng Lou ,
  • Fengwen Sun ,
  • Xiaojun An ,
  • Litao Zhi ,
  • Sanjun Huo ,
  • Juanjuan Zheng ,
  • Li Wang
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  • School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials, Huaiyin Normal University, Huai’an 223300

Received date: 2012-02-05

  Revised date: 2012-03-22

  Online published: 2012-04-10

Supported by

Project supported by Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials (JSKC11101 ).

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摘要

3-乙酰基香豆素、芳醛和醋酸铵在醋酸溶剂中经微波辐射, 一步合成了4-芳基-2,6-二(3,3'-香豆素基)吡啶衍生物,反应在5~8 分钟内完成,产率60~86%,具有反应时间短、操作简便和环境友好等优点.所以产物经红外光谱、氢谱、质谱和元素分析表征.

关键词： 3-乙酰基香豆素; 芳醛; 吡啶衍生物; 微波辐射

本文引用格式

周建峰 , 娄风文 , 孙小军 , 安礼涛 , 支三军 , 霍娟娟 , 郑丽 , 王星帅 . 微波辐射下一步合成4-芳基-2,6-二(3,3'-香豆素基)吡啶衍生物[J]. 有机化学, 2012 , 32(06) : 1112 -1115 . DOI: 10.6023/cjoc1202054

Abstract

A series of 3,3'-(4-arylpyridine-2,6-diyl)bis(2H-chromen-2-one) derviatives were synthesized by the one-pot three-component reaction of 3-acetyl coumarin, aromatic aldehydes, and ammonium acetate in acetic acid under microwave irradiation. The reactions were completed in 5～8 min with 60%～86% yields, and the procedure has the advantages of short reaction time, easy work-up and environmental begin. Their structures were confirmed by 1H NMR, IR, MS techniques and elemental analysis.

Key words： pyridine derivatives; 3-acetylcoumarin; aromatic aldehyde; microwave irradiation

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