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2012 , Vol. 32 >Issue 9: 1695 - 1699

DOI: https://doi.org/10.6023/cjoc1201311

研究论文

Lewis酸诱导芳基三氮烯为底物Stille偶联反应研究

  • 南光明 ,
  • 周均
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  • a 伊犁师范学院化学与生物科学学院 新疆凝聚态相变与微结构实验室 伊宁 835000;
    b 伊犁出入境检验检疫局综合技术服务中心 伊宁 835000

收稿日期: 2012-01-31

  修回日期: 2012-05-18

  网络出版日期: 2012-05-01

基金资助

国家自然科学基金(No.20962022)、新疆凝聚态相变与微结构实验室开放课题基金(No.2012YLSYnjt 01)资助项目

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Study on Lewis Acid Induced the Stille Cross-Coupling Reactions of Aryltriazenes as Substrates

  • Nan Guangming ,
  • Zhou Jun
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  • a Xinjiang Laboratory of Phase Transitions and Microstructures of Condensed Matters, College of Chemistry and Biology, Yili Normal University, Yining 835000;
    b Comprehensive Technical Service Centre of Yili Entry-exit Inspection and Quarantine Bureau, Yining 835000

Received date: 2012-01-31

  Revised date: 2012-05-18

  Online published: 2012-05-01

Supported by

Project supported by the National Natural Science Foundation of China (No.20962022), the Opening Project of Xinjiang Laboratory of Phase Transitions and Microstructures of Condensed Matters (No.2012YLSYnjt 01)

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摘要

首次以芳基三氮烯为新型亲电底物进行Stille偶联反应研究.反应在室温、氩气保护下进行.溶剂、两底物物质的量比、催化剂用量等影响收率的因素被优化,取得最佳的优化条件,获得较好的收率.芳基三氮烯通过助催化剂路易斯酸迁移到钯化合物,偶联反应由钯催化剂催化完成.产物纯化通过硅胶柱层析完成,结构被1H NMR,13C NMR确定.

关键词： 芳基三氮烯; 偶联反应; 三丁基苯基锡

本文引用格式

南光明 , 周均 . Lewis酸诱导芳基三氮烯为底物Stille偶联反应研究[J]. 有机化学, 2012 , 32(9) : 1695 -1699 . DOI: 10.6023/cjoc1201311

Abstract

The Stille cross-coupling reaction of aryltriazene as a novel electrophilic substrate has been realized for the first time. The reactions were performed at room temperature under an argon atmosphere. Solvents, molar ratio of aryltriazene/tributyl(phenyl)stannane, amount of catalyst were optimized and excellent yield was obtained. Aryltriazene via Lewis acid-assisted was transferred to palladium(II) compound. Cross-coupling reactions were catalyzed by palladium(II) compound. The products were purified via column chromatography on silica gel. Structures of all products were confirmed by 1H NMR and 13C NMR techniques.

Key words： aryltriazenes; cross-coupling reaction; tributyl(phenyl)stannane

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