介孔材料MCM-41催化吲哚与硝基烯Friedel-Crafts反应的研究
收稿日期: 2012-05-09
修回日期: 2012-06-08
网络出版日期: 2012-06-21
基金资助
国家自然科学基金(Nos. 20962018, 20862015, 20562011)资助项目.
Friedel-Crafts Reaction of Indoles with Nitroalkenes Catalyzed by Mesoporous Material MCM-41
Received date: 2012-05-09
Revised date: 2012-06-08
Online published: 2012-06-21
Supported by
Project supported by the National Natural Science Foundation of China (Nos. 20962018, 20862015, 20562011).
用介孔材料MCM-41催化吲哚与β-硝基烯发生Friedel-Crafts反应, 成功地合成了天然产物中广泛存在的3-取代吲哚衍生物. 该方法具有反应条件温和、操作简单以及环境友好、经济良好等优点, 其催化剂也可循环再用.
关键词： 介孔材料MCM-41; 吲哚衍生物; 催化; 硝基烯烃; Friedel-Crafts反应
陈永诚 , 谢绍雷 , 解正峰 . 介孔材料MCM-41催化吲哚与硝基烯Friedel-Crafts反应的研究[J]. 有机化学, 2012 , 32(10) : 1970 -1974 . DOI: 10.6023/cjoc201205010
The Frieldel-Crafts reaction of indole with β-nitrostyrenes catalyzed by MCM-41 was studied. Application of this reaction led to produce 3-substituted indole derivatives being wide present in natural products. The method has several advantages of mild reaction, condition handling-up easily, environmental friendly and economic effects. The catalyst can be also recycled.
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