含吡唑环的1,3,4-噁二唑类衍生物的合成及杀菌活性研究
收稿日期: 2012-08-20
修回日期: 2012-10-07
网络出版日期: 2012-10-12
基金资助
浙江省教育厅基金(No. Y200803060)资助项目.
Synthesis and Fungicidal Activity of 1,3,4-Oxadiazole Derivatives Containing Pyrazole Moiety
Received date: 2012-08-20
Revised date: 2012-10-07
Online published: 2012-10-12
Supported by
Project supported by the Program of Education Department of Zhejiang Province (No. Y200803060).
孙娜波 , 童建颖 , 武宏科 . 含吡唑环的1,3,4-噁二唑类衍生物的合成及杀菌活性研究[J]. 有机化学, 2013 , 33(01) : 101 -105 . DOI: 10.6023/cjoc201208019
A series of novel 1,3,4-oxadiazole derivatives were synthesized from acetylacetone, hydrazine hydrate by multi-step reactions. Their structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities against Corynespora cassiicola, Pseudomonas syringae pv. Lachrymans, Pseudoperonospora cubensis and Sclerotinia sclerotiorum in vivo, and the results indicated that some of the title compounds displayed excellent fungicidal activities.
Key words： 1,3,4-oxadiazole; pyrazole; synthesis; fungicidal activity
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