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2013 , Vol. 33 >Issue 03: 611 - 614

DOI: https://doi.org/10.6023/cjoc201211002

研究论文

双阳离子型室温离子液体中Suzuki偶联反应研究

  • 张传越 ,
  • 石若冰 ,
  • 陈才元 ,
  • 金传明
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  • 湖北师范学院污染物分析与资源化技术湖北省重点实验室 黄石 435002

收稿日期: 2012-11-01

  修回日期: 2012-11-22

  网络出版日期: 2012-11-26

基金资助

国家自然科学基金(No. 21171053)和湖北省教育厅基金(No. Z20102501)资助项目.

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Suzuki Cross-Coupling Reactions in Dicationic Room Temperature Ionic Liquid

  • Zhang Chuanyue ,
  • Shi Ruobing ,
  • Chen Caiyuan ,
  • Jin Chuanming
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  • Hubei Normal University, Hubei Province Key Laboratory of Pollutant Analysis and Reuse Technology, Huangshi 435002

Received date: 2012-11-01

  Revised date: 2012-11-22

  Online published: 2012-11-26

Supported by

Project supported by the National Natural Science Foundation of China (No. 21171053) and the Science Foundation of Hubei Provincial Department of Education (No. Z20102501).

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摘要

合成了具有钳子型的双咪唑阳离子核的室温离子液体2, 它的相转变温度为-51 ℃, 热力学分解温度为412 ℃, 利用该离子液体作反应溶剂研究了不同钯催化剂PdCl2, Pd(OAc)2, Pd-NHC配合物3存在下的Suzuki偶联反应. 结果表明: 在NaOAc作碱, 0.5 mol%的Pd-NHC配合物3存在下溴代苯衍生物与苯硼酸反应具有较高的活性, 产率可以达到85%以上, Pd-NHC配合物3催化剂能更好地负载在钳子型双阳离子核室温离子液体2中, 该反应体系能重复循环使用多次, 且分离简单、重现性强、环境友好.

关键词： 室温离子液体; Suzuki偶联反应; N-杂卡宾配合物; 钯

本文引用格式

张传越 , 石若冰 , 陈才元 , 金传明 . 双阳离子型室温离子液体中Suzuki偶联反应研究[J]. 有机化学, 2013 , 33(03) : 611 -614 . DOI: 10.6023/cjoc201211002

Abstract

Room temperature ionic liquid (RTIL) 2 with pincer bisimidazole cationic nuclei was prepared. Its phase transition and thermal decomposition temperature are -51 and 412 ℃, respectively. Suzuki reactions have been studied when different catalyst PdCl2, Pd(OAc)2, Pd-N-heterocyclic carbene complex 3 were used in RTIL 2. The results indicate that aryl bromide can react with phenylboronic acid in the yield of over 85% in the presence of NaOAc and 0.5 mol% Pd-NHC 3, and the loading capability of Pd-NHC 3 in RTIL 2 is best. This high efficient catalytic system is environmentally benign, recoverable and easily separated with products.

Key words： room temperature ionic liquids; Suzuki cross-coupling reactions; N-heterocyclic carbene complex; palladium

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