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2013 , Vol. 33 >Issue 04: 675 - 686

DOI: https://doi.org/10.6023/cjoc201301019

研究专题

铂催化的炔丙醇酯的重排反应以及三级胺氮原子邻位的C—H官能化反应的研究

  • 夏晓峰 ,
  • 李莲花 ,
  • 梁永民
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  • 兰州大学 功能有机分子化学国家重点实验室 兰州 730000

收稿日期: 2013-01-09

  修回日期: 2013-02-01

  网络出版日期: 2013-02-18

基金资助

国家自然科学基金(No. 21072080)资助项目.

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Platinum-Catalyzed the Rearrangement of Propargylic Esters and C—H Bond Functionalization Adjacent to the Nitrogen of Tertiary Amines

  • Xia Xiaofeng ,
  • Li Lianhua ,
  • Liang Yongmin
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  • State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000

Received date: 2013-01-09

  Revised date: 2013-02-01

  Online published: 2013-02-18

Supported by

Project supported by the National Natural Science Foundation of China (No. 21072080).

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摘要

对我们研究小组近几年在铂催化炔丙醇酯的重排反应以及三级胺氮原子邻位的C—H官能化反应方面取得的成果进行了阶段小结. 重点从反应的设计, 反应体系中的添加剂等对反应的影响, 讨论了不同底物中炔丙醇酯的重排方式, 并对相关反应机理进行了讨论. 同时我们首次提出了非氧化条件下铂催化的交叉脱氢偶联(CDC)反应.

关键词： 铂催化; 氧化脱氢反应; 串联反应; 重排反应

本文引用格式

夏晓峰 , 李莲花 , 梁永民 . 铂催化的炔丙醇酯的重排反应以及三级胺氮原子邻位的C—H官能化反应的研究[J]. 有机化学, 2013 , 33(04) : 675 -686 . DOI: 10.6023/cjoc201301019

Abstract

Our recent progress in platinum-catalyzed the rearrangement of propargylic esters and C—H bond functionalization adjacent to the nitrogen of tertiary amines is summaried. The effect of the design of the substrates and additives on these reactions is described, and the mechanisms of these reactions are also discussed. At the same time, the first oxidant-free cross-dehydrogenative coupling (CDC) reaction under platinum-catalysis is proposed.

Key words： platiunm-catalysis; oxidative dehydrogenation; tandem reaction; rearrangement

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