溴化二甲基溴化硫催化下合成N-取代吡咯类化合物
收稿日期: 2013-07-17
修回日期: 2013-09-02
网络出版日期: 2013-09-06
基金资助
天津市自然科学基金（Nos. 12JCZDJC34300，11JCYBJC03600）；青年科学基金（No. 21001080）资助项目.
Synthesis of N-Substituted Pyrroles Catalyzed by Bromodimethylsulfonium Bromide
Received date: 2013-07-17
Revised date: 2013-09-02
Online published: 2013-09-06
Supported by
Project supported by the Natural Science Foundation of Tianjin City (Nos. 12JCZDJC34300, 11JCYBJC03600), the Young Scientist Fund (No. 21001080).
室温、无溶剂条件下，以溴化二甲基溴化硫（BDMS）为催化剂，以2，5-己二酮和伯胺类化合物为原料，能高收率的实现一系列N-取代吡咯衍生物的合成. 所有化合物结构通过1H NMR，13C NMR和元素分析确定.
关键词： 吡咯; 溴化二甲基溴化硫（BDMS）; 合成
岳闽敏 , 刘巨艳 , 王英 , 袁斌 . 溴化二甲基溴化硫催化下合成N-取代吡咯类化合物[J]. 有机化学, 2014 , 34(1) : 190 -196 . DOI: 10.6023/cjoc201307026
A series N-substituted pyrroles were prepared efficiently in high yields by the condensation of 2,5-hexanedione with primary amines in the presence of bromodimethylsulfonium bromide (BDMS) at room temperature under solvent-free conditions. All products were characterized by 1H NMR, 13C NMR spectra and elemental analysis.
Key words： pyrroles; bromodimethylsulfonium bromide (BDMS); synthesis
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