吡咯并菲啶酮构建方法学研究进展
收稿日期: 2014-04-22
修回日期: 2014-05-29
网络出版日期: 2014-06-16
基金资助
国家自然科学基金（No. 21272276）和长江学者和创新团队发展计划（No. IRT1193）资助项目.
Recent Advances on Construction of Pyrrolophenanthridone Skeleton
Received date: 2014-04-22
Revised date: 2014-05-29
Online published: 2014-06-16
Supported by
Project supported by the National Natural Science Foundation of China (No. 21272276) and the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT1193).
丛蔚 , 徐进宜 , 姚和权 . 吡咯并菲啶酮构建方法学研究进展[J]. 有机化学, 2014 , 34(10) : 1966 -1977 . DOI: 10.6023/cjoc201404041
Pyrrolophenanthridone is a common structural motif existedexisting in a number of amaryllidaceae alkaloids, many of which possess a wide range of biological activities. The intriguing structural feature and significant biological activity have attracted much attention from synthetic communities. In the past decades, several excellent synthetic methodologies have been reported, in which intramolecular or intermolecular cross-coupling reaction through transition-metal catalyzed or radical pathway represents the most straightforward method for construction of this skeleton. This review focuses on the construction of pyrrolophenanthridone skeleton and total synthesis of amaryllidaceae alkaloids.
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