五个天然异戊烯基黄酮的首次全合成研究
收稿日期: 2014-06-14
修回日期: 2014-08-08
网络出版日期: 2014-08-26
基金资助
国家自然科学基金（Nos. 21162021，21362025）、教育部新世纪优秀人才支持计划（No. NCET-09-0860）资助项目.
First Total Synthesis of Five Natural Prenylated Flavonoids
Received date: 2014-06-14
Revised date: 2014-08-08
Online published: 2014-08-26
Supported by
Project supported by the National Natural Science Foundation of China (Nos. 21162021, 21362025) and the Program for New Century Excellent Talents in University (No. NCET-09-0860).
完成了具有2，3-二羟基-3-甲基丁基黄酮化合物brosimacutin A-B，brosimacutin D，brosimacutin E，brosimacutin H和brosimacutin M五个黄酮类化合物的消旋体的合成. 所有新化合物的结构都经过NMR，HRMS确认.
关键词： 异戊烯基黄酮; 查尔酮; 二氢查尔酮; 全合成; brosimacutin
冯尧 , 杨金会 , 马晓琴 , 陈兵兵 , 谢一民 . 五个天然异戊烯基黄酮的首次全合成研究[J]. 有机化学, 2014 , 34(10) : 2015 -2020 . DOI: 10.6023/cjoc201406018
A simple and efficient approach for synthesis flavonoids with 2,3-dihydroxy-3-methylbutyl moiety, by which seven natural prenylated flavonoids, brosimacutin A-B, brosimacutin D, brosimacutin E, brosimacutin H and brosimacutin M have been synthesized in racemic form. All structures of new compounds were confirmed by NMR and HRMS.
Key words： prenylated flavonoids; chalcone; dihydrochalcones; total synthetic; brosimacutin
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