1'-芳甲基二茂铁联烯的合成
收稿日期: 2015-02-08
修回日期: 2015-03-08
网络出版日期: 2015-03-13
基金资助
国家自然科学基金(No. 21262023)和内蒙古自治区杰出青年培育基金(No. 2014JQ02)资助项目
Synthesis of 1'-Arylmethyl-1-(1,2-dienyl)ferrocenes
Received date: 2015-02-08
Revised date: 2015-03-08
Online published: 2015-03-13
Supported by
Project supported by the National Natural Science Foundation of China (No. 21262023) and the Natural Science Foundation of Inner Mongolia of China (No. 2014JQ02).
设计了新型1'-芳甲基二茂铁联烯衍生物的合成方法, 该方法以方便易得的二茂铁为底物, 通过傅氏酰基化、还原、乙酰化、乙炔化及改进的Crabbé反应等过程, 合成了六种目标化合物. 并通过核磁共振氢谱、碳谱及高分辨质谱对其结构进行了表征.
关键词： 二茂铁; 联烯; 1'-芳甲基二茂铁联烯; 合成
王晨君 , 王晗 , 马超 , 张开新 , 韩飞 , 李保国 , 陈树峰 . 1'-芳甲基二茂铁联烯的合成[J]. 有机化学, 2015 , 35(7) : 1544 -1550 . DOI: 10.6023/cjoc201502013
A convenient procedure for synthesizing 1'-arylmethyl-1-(1,2-dienyl)ferrocene derivatives was explored. Using commercially available ferrocene as the starting material, the six target compounds were obtained in five steps via Friedel-Crafts acylation, reduction, acetylation, acetylene formation and modified Crabbé reaction. The structures of the obtained allenes were characterized by 1H NMR and 13C NMR and HRMS.
Key words： ferrocene; allene; 1'-arylmethyl-1-(1,2-dienyl)ferrocene; synthesis
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