异硫氰酸酯的合成改进
收稿日期: 2015-03-18
修回日期: 2015-04-16
网络出版日期: 2015-05-14
基金资助
国家自然科学基金(No. 21002009)、江苏省高校自然科学研究(Nos. 12KJA150002, 14KJA150002)、江苏省科技(BY2014037-01)和江苏省青蓝工程资助项目.
Improvement of the Synthesis of Isothiocyanates
Received date: 2015-03-18
Revised date: 2015-04-16
Online published: 2015-05-14
Supported by
Project supported by the National Natural Science Foundation of China (No. 21002009), the Major Program for the Natural Science Research of Jiangsu Colleges and Universities (Nos. 12KJA150002, 14KJA150002), the Scientific and Technological Project of Jiangsu Province (BY2014037-01), and the Qing Lan Project of Jiangsu Province.
李正义 , 石嵩 , 庄跃 , 郑崇谦 , 张金龙 , 孙小强 . 异硫氰酸酯的合成改进[J]. 有机化学, 2015 , 35(9) : 1999 -2003 . DOI: 10.6023/cjoc201503026
Isothiocyanates were prepared from the reactions of phenyl chlorothionoformate and various primary amines vis one-step or two-step process without additional base. The one-step process is good at highly active amines, while two-step approach is suitable for all kinds of amines. This method has many merits such as environment-friendly, easily available raw materials, low toxicity and convenient operation, which has a good application prospect in industry.
Key words： isothiocyanate; phenyl chlorothionoformate; primary amine; synthesis
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