一种新型1,3,4-噁二嗪酮化合物的合成及其晶体结构
收稿日期: 2015-09-25
修回日期: 2015-10-27
网络出版日期: 2015-11-06
基金资助
国家自然科学青年基金(No. 21106069)、南京科技职业学院院级重点(No. NHKY-2015-1)资助项目.
Synthesis and Crystal Structure of a Novel 1,3,4-Oxadiazin-one Compound
Received date: 2015-09-25
Revised date: 2015-10-27
Online published: 2015-11-06
Supported by
Project supported by the National Natural Science Foundation of China (No. 21106069) and the Key Program of Nanjing Polytechnic Institute (No. NHKY-2015-1).
孙宏顺 , 王建强 , 谭文文 , 杨海东 , 李玉龙 , 沈临江 , 郭成 . 一种新型1,3,4-噁二嗪酮化合物的合成及其晶体结构[J]. 有机化学, 2016 , 36(3) : 622 -625 . DOI: 10.6023/cjoc201509033
Using benzothiophene-2-carboxylic acid as a raw material, 2-(1-benzothiophen-2-yl)-4H-1,3,4-oxadiazin-5(6H)-one (4) was synthesized by esterification and hydrazinolysis, followed by the acylation and cyclization reactions. The novel compound 4 was characterized by 1H NMR, 13C NMR, ESI-MS, FT-IR, elemental analysis and X-ray single crystal diffraction.
Key words： benzothiophen; oxadiazin; synthesis; crystal structure
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