钯催化合成氧化芪三酚的研究
收稿日期: 2015-09-30
修回日期: 2015-12-03
网络出版日期: 2016-01-04
基金资助
湖南省自然科学基金(No.2015JJ3012)、湖南省教育厅(No.14C0050)和电力与交通材料保护湖南省重点实验室(No.2016CL01)资助项目.
Study on the Synthesis of Oxyresveratrol Catalyzed by Palladium
Received date: 2015-09-30
Revised date: 2015-12-03
Online published: 2016-01-04
Supported by
Project supported by the Natural Science Foundation of Hunan Province (No. 2015JJ3012), the Scientific Research Fund of Hunan Provincial Education Department (No. 14C0050) and Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation (2016CL01).
李志伟 , 康绍英 , 陈琳 , 王宇 , 李江胜 . 钯催化合成氧化芪三酚的研究[J]. 有机化学, 2016 , 36(5) : 1143 -1147 . DOI: 10.6023/cjoc201509046
A convenient method for the synthesis of oxyresveratrol catalyzed by palladium is described. 2,4-Dihydroxyiodo-benzene underwent Heck reaction with acrylic acid, then decarboxylation, and further underwent Heck reaction with 3,5-dihydroxyiodobenzene, furnishing oxyresveratrol in a high yield. The title compound was characterized by MS and NMR. This synthetic method has several advantages such as less step processes, high yield, simple operations, and promises to be applied in industrial production.
Key words： decarboxylation; oxyresveratrol; palladium catalysis; heck reaction
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