四丁基碘化铵催化的氧化脱氢反应选择性合成Z-β-酰胺基烯酮
收稿日期: 2016-01-27
修回日期: 2016-02-26
网络出版日期: 2016-03-18
基金资助
山西省科技攻关（No.20130313015-2）资助项目.
Tetra-butyl Ammonium Iodide-Catalyzed Oxidative Dehydrogenation for the Selective Synthesis of Z-β-Acylamino Enones
Received date: 2016-01-27
Revised date: 2016-02-26
Online published: 2016-03-18
Supported by
Project supported by the Science and Technology Key Project of Shanxi Province (No. 20130313015-2).
赵玉英 , 王二兵 , 王颖莉 . 四丁基碘化铵催化的氧化脱氢反应选择性合成Z-β-酰胺基烯酮[J]. 有机化学, 2016 , 36(7) : 1681 -1685 . DOI: 10.6023/cjoc201601034
A tetra-butyl ammonium iodide (TBAI)-catalyzed oxidative dehydrogenation of β-acylamino ketones for the synthesis of Z-β-acylamino enones has been developed. The present method has some distinct advantages such as mild conditions, high selectivity, readily available starting materials, and broad substrate scope. This method is also the first example of oxidative dehydrogenation with the use of TBAI/TBHP (tert-butyl hydroperoxide) oxidation system.
Key words： iodide; catalytic dehydrogenation; β-acylamino enones; stereoselectivity
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