离子液体中溴钯化启动的烯炔烃串联的氧化杂环化反应研究
收稿日期: 2016-03-27
修回日期: 2016-04-14
网络出版日期: 2016-05-17
基金资助
项目受国家自然科学基金（No.21502055），中央高校基本科研业务费（No.2015ZM150）和中国博士后科学基金（No.2015M572303）资助.
Bromopalladation Triggering the Cascade Oxidative Heterocyclization Reaction of Alkynes with Alkenes in Ionic Liquids
Received date: 2016-03-27
Revised date: 2016-04-14
Online published: 2016-05-17
Supported by
Project supported by the National Natural Science Foundation of China (No.21502055), the Fundamental Research Funds for the Central Universities (No.2015ZM150) and China Postdoctoral Science Foundation (No.2015M572303).
安艳妮 , 李建晓 , 张振明 , 李春生 , 杨少容 . 离子液体中溴钯化启动的烯炔烃串联的氧化杂环化反应研究[J]. 有机化学, 2016 , 36(9) : 2136 -2141 . DOI: 10.6023/cjoc201603043
An efficient and practical palladium-catalyzed cascade oxidative heterocyclization has been developed to afford functionalized oxygen-containing five-membered heterocycles in moderate to good yields with high regio- and diastereo-selectivities. Their structures were confirmed by IR, 1H NMR, 13C NMR and HRMS. Furthermore, the current methodology could also be conveniently applied to the synthesis of naturally occurring biologically active functionalized tetrahydrofurans and γ-lactones frameworks.
Key words： palladium-catalyzed; ionic liquids; alkynes; alkenes; heterocycles
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