一种2-烯基呋喃/噻吩的高效合成方法：高速球磨条件下的氧化Heck偶联反应
收稿日期: 2016-12-18
修回日期: 2017-02-08
网络出版日期: 2017-02-15
基金资助
国家重点基础研究发展计划（No.2014CB460608）和国家自然科学基金（Nos.21406201，21276237）资助项目.
An Efficient Synthesis of 2-Vinyl Furans/Thiophenes: Oxidative Heck Coupling under High-Speed Ball-Milling Conditions
Received date: 2016-12-18
Revised date: 2017-02-08
Online published: 2017-02-15
Supported by
Project supported by the Special Program for Key Basic Research of the Ministry of Science and Technology of China (No. 2014CB460608) and the National Natural Science Foundation of China (Nos. 21406201, 21276237).
贾侃彦 , 江之江 , 俞静波 , 洪子坤 , 苏为科 . 一种2-烯基呋喃/噻吩的高效合成方法：高速球磨条件下的氧化Heck偶联反应[J]. 有机化学, 2017 , 37(6) : 1473 -1478 . DOI: 10.6023/cjoc201612047
An efficient synthesis of 2-vinyl furans and thiophenes through oxidative Heck reaction has been explored under solvent-less high-speed ball-milling conditions. This Pd-catalyzed oxidative Heck reaction proceeded well with both acrylates and styrenes, which afford desired product in 45 min, with moderate to high yields.
Key words： high-speed ball-milling; oxidative Heck coupling; furan; thiophene
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