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2017 , Vol. 37 >Issue 6: 1443 - 1449

DOI: https://doi.org/10.6023/cjoc201612056

研究论文

聚乙二醇单甲醚修饰蒽化合物纯水相荧光识别Hg2＋及半胱氨酸

  • 李春涛 ,
  • 王蒙蒙 ,
  • 朱倩 ,
  • 曹迁永
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  • 南昌大学化学学院 鄱阳湖环境与资源利用教育部重点实验室 南昌 330031

收稿日期: 2016-12-23

  修回日期: 2017-01-25

  网络出版日期: 2017-02-20

基金资助

国家自然科学基金（No.21462027资助项目.

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A New Methoxy Poly(ethylene glycol)-anchored Anthracene for Fluorescence Sensing of Hg2＋and Subsequent of Cysteine in Pure Aqueous Solution

  • Li Chuntao ,
  • Wang Mengmeng ,
  • Zhu Qian ,
  • Cao Qianyong
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  • Key Laboratory of Poyang Lake Environment and Resource Utilization, Ministry of Education, Department of Chemistry, Nanchang University, Nanchang 330031

Received date: 2016-12-23

  Revised date: 2017-01-25

  Online published: 2017-02-20

Supported by

Project supported by the National Natural Science Foundation of China (No 21462027).

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摘要

通过点击反应合成了一种聚乙二醇单甲醚（mPEG）修饰含蒽荧光团及二（2-吡啶甲基）胺（DPA）金属离子识别位点水溶性高分子化合物P1.在纯水溶液中，P1能够与Hg2＋形成稳定的1：1型配合物P1-Hg2＋，伴随着聚合物P1荧光猝灭.同时，P1-Hg2＋络合物对半胱氨酸（Cys）有很好的选择性识别.随着Cys浓度的增加，由于Cys与Hg2＋结合，使得P1的荧光得到恢复，且不受其它氨基酸的干扰.

关键词： PEG; 荧光; 半胱氨酸识别; 蒽; Hg2＋

本文引用格式

李春涛 , 王蒙蒙 , 朱倩 , 曹迁永 . 聚乙二醇单甲醚修饰蒽化合物纯水相荧光识别Hg2＋及半胱氨酸[J]. 有机化学, 2017 , 37(6) : 1443 -1449 . DOI: 10.6023/cjoc201612056

Abstract

A new Methoxy poly(ethylene glycol)-anchored polymer sensor P1, which contains anthracene fluorephore and di-2-picolylamine metal ions binding site, has been easily synthesized by "click reaction". In pure aqueous solution, P1 can coordinate with Hg2＋ quickly to form 1:1 stoichiometry P1-Hg2＋ complex, with quenching the fluorescence of P1. In addition, P1-Hg2＋ shows exclusive fluorescence turn-on sensing of cysteine (Cys) over other amino acids for the displacement method.

Key words： PEG; fluorescence; Cys recognition; anthracene; Hg2＋

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