官能团化香豆素并[4,3-d]吡唑并[3,4-b]吡啶衍生物的合成及其对锌离子的选择性识别
收稿日期: 2017-02-23
修回日期: 2017-04-17
网络出版日期: 2017-05-02
基金资助
国家自然科学基金（No.21502074）和江苏省高校自然科学重大研究（No.15KJA150006）资助项目.
Synthesis of Functionalized Coumarino[4,3-d]pyrazolo[3,4-b]pyridine Derivatives and Their Selective Recognition for Zn2+
Received date: 2017-02-23
Revised date: 2017-04-17
Online published: 2017-05-02
Supported by
Project supported by the National Natural Science Foundation of China (No. 21502074) and the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions (No. 15KJA150006).
在硫酸铜催化下，通过3-乙酰乙酰基香豆素与5-氨基吡唑的加成环化反应合成了一系列官能团化的香豆素并[4，3-d]吡唑并[3，4-b]吡啶衍生物3a~3h.合成得到的部分化合物具有很高的荧光量子产率.利用荧光光谱考察了其与Ag+、Cr3+、Co2+、Cu2+、Pb2+、Sn4+、Fe3+、Zn2+等金属离子的作用，结果表明化合物3a和3b对Zn2+具有很好的选择性识别能力.
关键词： 香豆素并[4,3-d]吡唑并[3,4-b]吡啶衍生物; 合成; 荧光性质; 锌离子; 选择性识别
林伟 , 蔡琦 , 郑纯智 , 郑永祥 , 史达清 . 官能团化香豆素并[4,3-d]吡唑并[3,4-b]吡啶衍生物的合成及其对锌离子的选择性识别[J]. 有机化学, 2017 , 37(9) : 2392 -2398 . DOI: 10.6023/cjoc201702032
A series of functionalized coumarino[4,3-d]pyrazolo[3,4-b]pyridine derivatives 3a~3h were synthesized by the addition and cyclization of 3-acetoacetylcoumarin with 5-aminopyrazole catalyzed by CuSO4. Some of the synthesized compounds had high fluorescence quantum yields. The properties of the compounds with cations such as Ag+, Cr3+, Co2+, Cu2+, Pb2+, Sn4+, Fe3+ and Zn2+ were examined by fluorescence spectroscopy. The results showed that compounds 3a and 3b have selective recognition for Zn2+.
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