亚胺基吡咯酮类化合物的合成
收稿日期: 2017-05-02
修回日期: 2017-06-16
网络出版日期: 2017-06-23
基金资助
国家自然科学基金（Nos.21362042，21662042，U1202221，21262042）、云南省自然科学基金（No.2017FA003）、云南省后备人才（2012HB001）、云南大学东陆学者，云南大学青年英才计划资助项目（No.XT412003）.
Synthesis of Iminopyrrolone Compounds
Received date: 2017-05-02
Revised date: 2017-06-16
Online published: 2017-06-23
Supported by
Project supported by the National Natural Science Foundation of China (Nos.21362042,21662042,U1202221,21262042),the Natural Science Foundation of Yunnan Province (No.2017FA003),the Talent Found in Yunnan Province (No.2012HB001),the Donglu Scholar of Yunnan University and the Excellent Young Talents in Yunnan University (No.XT412003).
赵宇澄 , 肖强 , 王保取 , 林军 , 严胜骄 . 亚胺基吡咯酮类化合物的合成[J]. 有机化学, 2017 , 37(10) : 2690 -2696 . DOI: 10.6023/cjoc201705004
The method was constructed for synthesis of pyrrolone compounds, which was based on the reaction of 1,1-endiamine (1) with maleic anhydride (2) in 1,4-dioxane at reflux in alkali condition (Et3N). As a result, a series of iminopyrrolone compounds have been synthesized by this reaction. This protocol possesses some advantages including readily available starting materials, simple operation and concise synthetic route and so on.
Key words： iminopyrrolone; nitro-enamine; synthesis
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