新型含七氟异丙基结构的吡唑酰胺类化合物的合成与杀虫活性研究
收稿日期: 2017-07-20
修回日期: 2017-08-15
网络出版日期: 2017-08-18
基金资助
国家自然科学基金（No.21372135）、江苏省“六大人才高峰”（No.2013-SWYY-013）、南通市科技计划（No.MS22015020）、江苏省大学生创新训练计划（No.201610304047Z）和南通大学研究生科研创新计划（No.YKC16086）资助项目.
Synthesis and Insecticidal Activities of Novel Pyrazole Amides Containing Heptafluoroisopropyl Moiety
Received date: 2017-07-20
Revised date: 2017-08-15
Online published: 2017-08-18
Supported by
Project supported by the National Natural Science Foundation of China (No. 21372135), the Research Foundation of the Six People Peak of Jiangsu Province (No. 2013-SWYY-013), the Science and Technology Project Fund of Nantong City (No. MS22015020), the Science and Technology Innovation Foundation for the College Students of Jiangsu Province (No. 201610304047Z) and the Science and Technology Innovation Foundation for the Graduate Students of Nantong University (No. YKC16086).
洪宇 , 戴红 , 叶林玉 , 仲苏林 , 曹雄飞 , 石玉军 , 李春建 , 石健 , 施磊 . 新型含七氟异丙基结构的吡唑酰胺类化合物的合成与杀虫活性研究[J]. 有机化学, 2017 , 37(11) : 3006 -3012 . DOI: 10.6023/cjoc201707022
In order to find new pyrazole derivatives with potent biological activities, a series of novel pyrazole amides containing heptafluoroisopropyl moiety were prepared according to the method of active substructure combination. Their structures were characterized by 1H NMR, 13C NMR and elemental analysis. Preliminary bioassay data showed that some target compounds displayed good insecticidal activities. At the concentration of 500 μg/mL, eleven compounds had insecticidal activity against Oriental armyworm of 60%~100%. When the concentration was reduced to 100 μg/mL, three compounds showed insecticidal activity against Oriental armyworm of 60%~70%, better than that of the control tolfenpyrad.
Key words： heptafluoroisopropyl; pyrazole; synthesis; insecticidal activity
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