不饱和螺环缩酮的合成及对桔小实蝇(Bactrocera dorsalis)性引诱活性与构效关系研究
收稿日期: 2018-08-20
修回日期: 2018-09-29
网络出版日期: 2018-11-12
基金资助
国家自然科学基金（Nos.21572068，21871094）资助项目.
Synthesis, Biological Evaluation, and Structure-Activity Relationship Study of Unsaturated Spiroacetals as Potential Sex Attractants to Oriental Fruit Flies (Bactrocera dorsalis)
Received date: 2018-08-20
Revised date: 2018-09-29
Online published: 2018-11-12
Supported by
Project supported by the National Natural Science Foundation of China (Nos. 21572068, 21871094).
李九一 , 陈立 , 尹标林 . 不饱和螺环缩酮的合成及对桔小实蝇(Bactrocera dorsalis)性引诱活性与构效关系研究[J]. 有机化学, 2019 , 39(3) : 747 -753 . DOI: 10.6023/cjoc201808022
Spiroacetal motif is widely distributed in many bioactive natural products of different origins and essentially contributes to various bioactivities. In this paper, two series of spiroacetals were synthesized and biologically evaluated as insect sex attractant towards oriental fruit flies (Bactrocera dorsalis) using methyleugenol as the standard. Biological evaluation demonstrated that a large part of the tested compounds triggered apparent electrophysiological responses from both male and female fruit flies. The stereochemistry of the spiroacetals and the substitution on their phenyl rings influenced the responses to some degree.
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