可见光催化环丙基胺与1,2-二酮衍生物的[3+2]环加成反应
收稿日期: 2019-02-21
修回日期: 2019-03-27
网络出版日期: 2019-04-11
基金资助
国家自然科学基金（No.21572184）、福建省自然科学基金（No.2017J06006）、中央高校基本科研业务费（No.20720160027）资助项目.
Visible-Light-Induced[3+2] Annulation of Cyclopropylamines with 1,2-Diketone Derivatives
Received date: 2019-02-21
Revised date: 2019-03-27
Online published: 2019-04-11
Supported by
Project supported by the National Natural Science Foundation of China (No. 21572184), the Natural Science Foundation of Fujian Province (No. 2017J06006), and the Fundamental Research Funds for the Central Universities (No. 20720160027).
报道了一种可见光催化环丙基胺与1，2-二芳基乙二酮衍生物的[3+2]环加成反应，合成了一系列α-氨基呋喃衍生物，该反应条件温和，产率良好，操作简单.这一方法为潜在生物活性分子骨架α-氨基呋喃衍生物的合成提供了一条高效便捷的路径.
关键词： 光氧化还原; 环丙基胺; 1,2-二酮衍生物; [3+2]环加成反应
代雪梅 , 李延军 , 张少南 , 龚磊 . 可见光催化环丙基胺与1,2-二酮衍生物的[3+2]环加成反应[J]. 有机化学, 2019 , 39(6) : 1711 -1719 . DOI: 10.6023/cjoc201902022
A visible-light-induced[3+2] annulation of arylcyclopropylamines and 1,2-diarylethanediones was report. A series of α-amino tetrahydrofuran derivatives were synthesized in moderate to good isolated yields under mild reaction conditions. This method would provide an efficient and convenient approach to α-amino tetrahydrofurans which are potentially important buiding blocks in bioactive compounds.
Key words： photoredox; cyclopropylamines; 1,2-diketone derivatives; [3+2] annulation
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