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2019 , Vol. 39 >Issue 10: 2980 - 2984

DOI: https://doi.org/10.6023/cjoc201904001

研究简报

含巴比妥结构荧光探针的合成及其应用研究

  • 刘钰 ,
  • 汤永星 ,
  • 罗月阳 ,
  • 朱叶婷 ,
  • 杨进 ,
  • 魏欣雨 ,
  • 刘雄 ,
  • 赵云辉
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  • a 河南工业大学小麦和玉米深加工国家工程实验室 郑州 450001
    b 中国科学院上海有机化学研究所 天然产物有机合成化学重点实验室 上海 200032
    c 湖南科技大学化学化工学院 精细聚合物可控制备及功能应用湖南省重点实验室 湘潭 411201

收稿日期: 2019-04-01

  修回日期: 2019-05-05

  网络出版日期: 2019-05-21

基金资助

河南工业大学小麦和玉米深加工国家工程实验室开放课题(No. NL2018006)

收起

Synthesis and Application of Fluorescent Probe Containing Barbitone Unit

  • Yu Liu, ,
  • Yongxing Tang, ,
  • Yueyang Luo, ,
  • Yeting Zhu, ,
  • Jin Yang, ,
  • Xinyu Wei, ,
  • Xiong Liu, ,
  • Yunhui Zhao,
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  • a National Engineering Laboratory for Wheat & Corn Further Processing, Henan University of Technology, Zhengzhou 450001;
    b Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
    c Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201

Received date: 2019-04-01

  Revised date: 2019-05-05

  Online published: 2019-05-21

Supported by

Project supported by the Open Project of the National Engineering Laboratory for Wheat & Corn Further Processing, Henan University of Technology(No. NL2018006)

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摘要

汞离子污染已经严重危害生态环境和人类健康, 发展具有高选择性、高灵敏度且能应用于水性环境中汞离子的检测探针具有重要的研究意义. 以水杨醛为原料, 设计、合成一种含有巴比妥结构单元的激发态分子内质子转移(ESIPT)型荧光探针; 机理研究预测汞离子与探针形成了一种类似于“(胸腺嘧啶)T-Hg-T”的结构, 从而可以高选择性地识别汞离子, 并且在4~20 μmol·L –1之间, 探针的荧光强度与汞离子浓度呈现非常好的线性关系.

关键词： 荧光探针; 汞离子; 巴比妥; 激发态分子内质子转移(ESIPT)

本文引用格式

刘钰 , 汤永星 , 罗月阳 , 朱叶婷 , 杨进 , 魏欣雨 , 刘雄 , 赵云辉 . 含巴比妥结构荧光探针的合成及其应用研究[J]. 有机化学, 2019 , 39(10) : 2980 -2984 . DOI: 10.6023/cjoc201904001

Abstract

Mercury ion pollution has serious harmful impact on the ecological environment and human health. It is of great significance to develop a probe with high selectivity and sensitivity that could be applied to the detection of mercury ion in water environment. In this paper, a novel excited-state intramolecular proton transfer (ESIPT) fluorescent probe containing barbitone unit was designed and synthesized from salicylaldehyde. Mechanism studies showed that mercury ions and probes formed a structure similar to “(thymine)T-Hg-T” which has high selectivity in determining mercury ions. The calibration curve indicated that there was a good linear correlation between the relative fluorescent intensities over the concentration range of 4~20 μmol·L –1 of Hg 2+ ion.

Key words： fluorescent probe; mercury ion; barbitone; excited-state intramolecular proton transfer (ESIPT)

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