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2020 , Vol. 40 >Issue 7: 1847 - 1859

DOI: https://doi.org/10.6023/cjoc202002025

综述与进展

硒化合物荧光传感器研究进展

  • 张继东 ,
  • 詹妍 ,
  • 李胡月雯 ,
  • 齐怡 ,
  • 王瑞鹏 ,
  • 孟莉
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  • a 安康学院化学化工学院 陕西省富硒食品质量监督检验中心 新型材料研究中心 陕西安康 725000;
    b 中国富硒产业研究院 农业农村部富硒产品开发与质量控制重点实验室 陕西安康 725000

收稿日期: 2020-02-19

  修回日期: 2020-04-09

  网络出版日期: 2020-04-23

基金资助

陕西省青年科学基金（No.2019JQ-504）、农业部富硒产品开发国家地方联合工程实验室开放课题（No.Se-2018B02）、安康学院博士科研启动基金（No.2018AYQDZR06）和国家级大学生创新创业训练计划（Nos.201911397007，201911397016）资助项目.

收起

Recent Progress in Fluorescent Chemosensors for Selenium Compounds

  • Zhang Jidong ,
  • Zhan Yan ,
  • Li-Hu Yuewen ,
  • Qi Yi ,
  • Wang Ruipeng ,
  • Meng Li
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  • a Quality Supervision and Inspection Centre of Se-Enriched Food of Shaanxi Province, Research Centre of New Materials, School of Chemistry & Chemical Engineering, Ankang Univerisity, Ankang, Shaanxi 725000;
    b Key Laboratory of Se-Enriched Products Development and Quality Control of Ministry of Agriculture, Se-Enriched Products Research Institute of China, Ankang, Shaanxi 725000

Received date: 2020-02-19

  Revised date: 2020-04-09

  Online published: 2020-04-23

Supported by

Project supported by the Youth Foundation of Shaanxi Provincial Science & Technology Department (No. 2019JQ-504), the Key Laboratory of Se-Enriched Products Development and Quality Control, Ministry of Agriculture (No. Se-2018B02), the Doctor's Initial Funding of Ankang University (No. 2018AYQDZR06) and the National Undergraduate Training Program for Innovation and Entrepreneurship (Nos. 201911397007, 201911397016).

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摘要

硒（Se）在生命体内是一种重要的微量元素，含有硒的蛋白质在哺乳动物体内具有广泛的生物学效应，如抗氧化、抗炎和促进产生甲状腺激素等作用.在过去的几十年里，含硒物质因其在生物体内的生物活性而引起人们的极大关注，其主要归因于Se元素的氧化还原及软硬质子性能.近年来，随着荧光检测技术的发展，大量硒化合物荧光传感器被开发出来.主要综述了含硒物质如硒代半胱氨酸（Sec）、硒化氢、硒醇和Se（IV）等荧光传感器的研究进展，并对其研究前景进行了展望.

关键词： 硒化合物; 荧光传感器; 生物成像; 荧光检测; 纳米颗粒

本文引用格式

张继东 , 詹妍 , 李胡月雯 , 齐怡 , 王瑞鹏 , 孟莉 . 硒化合物荧光传感器研究进展[J]. 有机化学, 2020 , 40(7) : 1847 -1859 . DOI: 10.6023/cjoc202002025

Abstract

Selenium (Se) is an important trace element in life and has been associated with many diseases. Protein containing selenium has a wide range of biological effects, such as antioxidant, anti-inflammatory and promotes the production of thyroid hormone action. In the past few decades, selenium has attracted great attention because of its important role in biology, which is mainly attributed to the redox of Se elements and the properties of hard and soft protons. In recent years, with the development of chemical simulation technology, a large number of selenium-related fluorescent chemosensors have been developed to monitor physiological and pathological processes. Fluorescent chemosensors containing selenium materials, such as selenocysteine (Sec), hydrogen selenide and Se(IV) are reviewed. The development tendency of the sensing Se compounds is prospected.

Key words： Se compound; fluorescent sensor; bioimaging; fluorescent detection; nanoparticle

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