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2020 , Vol. 40 >Issue 9: 2702 - 2713

DOI: https://doi.org/10.6023/cjoc202003064

综述与进展

介离子化合物的合成与生物活性研究进展

  • 梁伟 ,
  • 谭成侠 ,
  • 翁建全 ,
  • 刘幸海
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  • 浙江工业大学化学工程学院 杭州 310014

收稿日期: 2020-03-29

  修回日期: 2020-05-13

  网络出版日期: 2020-06-01

基金资助

浙江省自然科学基金（No.LY19C140002）资助项目.

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Advances on Synthesis and Biological Activities of Mesoionic Compounds

  • Liang Wei ,
  • Tan Chengxia ,
  • Weng Jianquan ,
  • Liu Xinghai
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  • College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014

Received date: 2020-03-29

  Revised date: 2020-05-13

  Online published: 2020-06-01

Supported by

Project supported by the Natural Science Foundation of Zhejiang Province (No. LY19C140002).

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摘要

介离子化合物代表了一类在杂环化学中非常重要的分子，在医药和农药等领域有着广泛的应用.自1935年该类化合物被发现以来，因其有着独特的反应活性和物活性，人们对其合成、应用和性质等方面一直进行研究，不少文献报道了该类化合物的合成及相关活性.综述了几类介离子化合物的合成方法和部分重要机理，并探讨了介离子化合物作为一种优势活性结构在未来的应用前景.

关键词： 介离子化合物; 合成; 生物活性

本文引用格式

梁伟 , 谭成侠 , 翁建全 , 刘幸海 . 介离子化合物的合成与生物活性研究进展[J]. 有机化学, 2020 , 40(9) : 2702 -2713 . DOI: 10.6023/cjoc202003064

Abstract

As an important kind of heterocyclic molecules, mesoionic compounds are widely used in medicine, pesticide and other fields. Ever since they were discovered in 1935, mesoionic compounds have been extensively explored in terms of synthesis, properties and applications. Many references relating to these compounds have been published over years revealing their unique reactivity and bioactivity. An overview of mesoionic compounds from the perspectives of synthetic methods, reaction mechanisms and applications is offered. Their potentials as a dominant active structure for development of pesticides are also discussed.

Key words： mesoionic compound; synthesis; biological activity

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