中环大环化合物合成研究进展
收稿日期: 2020-10-18
修回日期: 2020-11-30
网络出版日期: 2020-12-10
基金资助
大学生创新创业(201910613081)
Recent Progress in the Synthesis of Medium-Sized Ring and Macrocyclic Compounds
Received date: 2020-10-18
Revised date: 2020-11-30
Online published: 2020-12-10
Supported by
Student's Platform for Innovation and Entrepreneurship Training Program(201910613081)
张馨元 , 林礼 , 李静 , 段世妤 , 隆宇航 , 李加洪 . 中环大环化合物合成研究进展[J]. 有机化学, 2021 , 41(5) : 1878 -1887 . DOI: 10.6023/cjoc202010026
Medium-sized rings (8~11 membered ring) and macrocycles (12-membered rings and above) are extremely important parts of drug and natural products. Meanwhile, they are widely used in the field of medicinal chemistry, organic chemistry and other fields. Developing simple, green and efficient protocol to synthesize medium-sized rings and macrocycles has attracted great interests from chemists in the recent years. The latest ring expansion/cyclization reaction in the synthesis of medium-sized ring and macrocyclic compounds in the past five years is reviewed, and the prospect of their future and development is also outlined.
Key words： medium-sized ring; macrocycle; ring expansion reaction; cyclization
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