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2021 , Vol. 41 >Issue 6: 2354 - 2360

DOI: https://doi.org/10.6023/cjoc202101017

研究论文

电化学介导的S—N键形成: 次磺酰胺化合物的简洁合成

  • 何慕雪 ,
  • 程诗砚 ,
  • 潘永周 ,
  • 唐海涛 ,
  • 潘英明
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  • 广西师范大学化学与药学学院 药物资源化学与分子工程国家重点实验室 广西桂林 541004

收稿日期: 2021-01-11

  修回日期: 2021-03-04

  网络出版日期: 2021-03-22

基金资助

国家自然科学基金(22061003)

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Electrochemically Mediated S—N Bond Formation: Synthesis of Sulfenamides

  • Muxue He ,
  • Shiyan Cheng ,
  • Yongzhou Pan ,
  • Haitao Tang ,
  • Yingming Pan
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  • State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, Guangxi 541004
*Corresponding authors.E-mail:;

Received date: 2021-01-11

  Revised date: 2021-03-04

  Online published: 2021-03-22

Supported by

National Natural Science Foundation of China(22061003)

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摘要

通过电氧化苯硫酚和胺合成了一系列次磺酰胺化合物. 该电合成反应无需金属催化剂和氧化剂, 采用简单的装置如单室电解槽, 并且使用恒电流电解, 具有底物范围广、原料简单易得、操作简便和环境友好等优点, 为结构多样的次磺酰胺的合成提供了简洁的新策略.

关键词： 次磺酰胺; 有机电合成; S—N键形成; 脱氢偶联

本文引用格式

何慕雪 , 程诗砚 , 潘永周 , 唐海涛 , 潘英明 . 电化学介导的S—N键形成: 次磺酰胺化合物的简洁合成[J]. 有机化学, 2021 , 41(6) : 2354 -2360 . DOI: 10.6023/cjoc202101017

Abstract

A series of sulfenamide compounds are synthesized by electrooxidation of thiophenols and amines. The electrosynthesis reaction does not require metal catalysts and oxidizing reagents, and uses simple devices such as single- chamber electrolyzers and constant current electrolysis. This method featured broad substrate scope, ready availability of starting materials, operational simplicity and environmental friendly, which provides a new strategy for the simple and convenient synthesis of various sulfenamide derivatives.

Key words： sulfenamides; organic electrosynthesis; S—N bond formation; dehydrogenative coupling

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