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2021 , Vol. 41 >Issue 11: 4361 - 4369

DOI: https://doi.org/10.6023/cjoc202107037

研究论文

钌选择性催化烯丙醇无受体脱氢合成α,β-不饱和羰基化合物

  • 刘嘉豪 ,
  • 张世冬 ,
  • 栾自鸿 ,
  • 刘艳 ,
  • 柯卓锋
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  • a 中山大学材料科学与工程学院 聚合物复合材料及功能材料教育部重点实验室 广州 510006
    b 广东工业大学轻工化工学院 广州 510006
† 共同第一作者.

收稿日期: 2021-07-16

  修回日期: 2021-08-15

  网络出版日期: 2021-08-25

基金资助

国家自然科学基金(21973113); 国家自然科学基金(21977019); 广东省自然科学杰出青年基金(2015A030306027)

收起

Ruthenium Catalyzed Selective Acceptorless Dehydrogenation of Allylic Alcohols to α,β-Unsaturated Carbonyls

  • Jiahao Liu ,
  • Shidong Zhang ,
  • Zihong Luan ,
  • Yan Liu ,
  • Zhuofeng Ke
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  • a Key Laboratory for Polymeric Composite & Functional Materials of Ministry of Education, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou 510006
    b School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006
† These authors contributed equally to this work.
* Corresponding author. E-mail:

Received date: 2021-07-16

  Revised date: 2021-08-15

  Online published: 2021-08-25

Supported by

National Natural Science Foundation of China(21973113); National Natural Science Foundation of China(21977019); Guangdong Natural Science Funds for Distinguished Young Scholar(2015A030306027)

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摘要

过渡金属催化烯丙醇的选择性脱氢氧化以得到相应的α,β-不饱和羰基化合物在最近广受关注, 但是很多方法需要用到化学计量的氧化剂, 这会带来大量的废弃副产物, 原子经济性不足. 本工作开发了一种简单易得的[RuCl2(p- cymene)]2催化系统, 可用于高效地催化烯丙醇选择性脱氢合成α,β-不饱和羰基化合物, 而无需使用额外的氧化剂或H2受体.

关键词： 钌; 无受体脱氢; 烯丙醇; α,β-不饱和羰基化合物

本文引用格式

刘嘉豪 , 张世冬 , 栾自鸿 , 刘艳 , 柯卓锋 . 钌选择性催化烯丙醇无受体脱氢合成α,β-不饱和羰基化合物[J]. 有机化学, 2021 , 41(11) : 4361 -4369 . DOI: 10.6023/cjoc202107037

Abstract

Transition metal-catalyzed allyllic alcohol selective dehydrogenation to generate the corresponding α,β-unsaturated carbonyl compound has attached great attention. However, most of these methods require stoichiometric quantities of oxidants, which will bring a lot of by-products and lack of atomic economy. Herein, a simple [RuCl2(p-cymene)]2 catalyzed system to efficiently catalyze the selective dehydrogenation of allyl alcohol to form α,β-unsaturated carbonyls without the use of additional oxidants or H2 acceptors has been developed.

Key words： ruthenium; acceptorless dehydrogenation; allylic alcohols; α,β-unsaturated carbonyls

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