一种连续识别Cu2+和草甘膦荧光探针的合成及应用研究
收稿日期: 2021-09-29
修回日期: 2021-10-28
网络出版日期: 2021-11-25
基金资助
国家自然科学基金(21908034); 黑龙江省自然科学基金(LH2021H001)
Synthesis and Application of a Novel Fluorescent Probe for Sequential Recognition Cu2+ and Glyphosate
Received date: 2021-09-29
Revised date: 2021-10-28
Online published: 2021-11-25
Supported by
National Natural Science Foundation of China(21908034); Natural Science Foundation of Heilongjiang Province(LH2021H001)
以7-(4-甲氧基苯基)乙炔基香豆素为荧光基团, 设计并合成了一种香豆素酰腙类荧光探针L. 在探针L的二甲基亚砜(DMSO)/H2O [V:V=7:3, 4-羟乙基哌嗪乙磺酸(HEPES) 10 mmol/L, pH=7.4]溶液中加入Cu2+, 可以通过肉眼观察到颜色由黄色变为浅棕色和明显的荧光猝灭效应. 该探针不受其他金属离子和阴离子的干扰, 检测限为5.6×10–8 mol/L. 同时, L-Cu2+体系通过配体置换的方式实现了对草甘膦的特异性检测, 具有良好的选择性和抗干扰性、较高的灵敏度、较宽的pH适用范围(5~9)和较低的检测限(11.3 ng/mL). 此外, L-Cu2+体系可应用于实际水样中草甘膦的检测, 在环境监测等领域具有良好的应用前景.
吴绵园 , 喻艳超 , 刘洋 , 由君 , 武文菊 , 刘波 . 一种连续识别Cu2+和草甘膦荧光探针的合成及应用研究[J]. 有机化学, 2022 , 42(3) : 803 -811 . DOI: 10.6023/cjoc202109049
A novel fluorescent probe L based on coumarin-derived acylhydrazone was designed and synthesized by using 7-(4-methoxyphenyl)ethynyl coumarin as report group. The probe L showed high selectivity and good anti-interference ability towards Cu2+ ion through the color of solution changed from light brown to yellow for naked-eye detection and significant fluorescence intensity quenched in the dimethyl sulfoxide (DMSO)/H2O [V:V=7:3, 2-[4-(2-hydroxyethyl)piperazin-1- yl]ethanesulfonic acid (HEPES) 10 mmol/L, pH=7.4] solution, and the detection limit of probe L to Cu2+ could reach 5.6×10–8 mol/L. Meanwhile, the L-Cu2+ system has high selectivity, good sensitivity, wide pH range (5~9) and low detection limit (11.3 ng/mL) for the detection of glyphosate by ligand replacement method. In addition, glyphosate detection was assessed within the actual water samples for testing the L-Cu2+actual application and the method was expected to the detection in environmental samples.
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