研究简报

棕榈花中两个新的莽草酸类化合物

  • 林芳霞 ,
  • 王治鸿 ,
  • 代德财 ,
  • 周学明 ,
  • 吴禄勇
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  • a 海南师范大学化学与化工学院 热带药用资源化学教育部重点实验室 海口 571158
    b 海南科技职业大学 海南省药食同源植物资源重点实验室 海口 571126
    c 海南师范大学化学与化工学院 热带药用植物化学海南省重点实验室 海口 571158
† 共同第一作者

收稿日期: 2021-09-29

  修回日期: 2021-11-22

  网络出版日期: 2021-12-22

基金资助

海南省自然科学基金(220QN252); 海南省自然科学基金(218QN234)

Two New Shikimic Acid Derivatives from the Flower of Trachycarpus fortunei

  • Fangxia Lin ,
  • Zhihong Wang ,
  • Decai Dai ,
  • Xueming Zhou ,
  • Luyong Wu
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  • a Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158
    b Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province, Hainan Vocational University of Science and Technology, Haikou 571126
    c Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158
† These authors contributed equally to this work.

Received date: 2021-09-29

  Revised date: 2021-11-22

  Online published: 2021-12-22

Supported by

Hainan Provincial Natural Science Foundation(220QN252); Hainan Provincial Natural Science Foundation(218QN234)

摘要

从棕榈花中分离鉴定了2个新的莽草酸衍生物以及4个生源相关的莽草酸衍生物. 综合运用多种波谱技术以及化学反应确定了所得化合物的结构. 所有分离得到的化合物均具有α-葡萄糖苷酶抑制活性, 其中trachshikimic B (2), 3-feruloylquinic acid (5)和chlorogenic acid (6)的活性强于阳性对照阿卡波糖.

本文引用格式

林芳霞 , 王治鸿 , 代德财 , 周学明 , 吴禄勇 . 棕榈花中两个新的莽草酸类化合物[J]. 有机化学, 2022 , 42(4) : 1248 -1251 . DOI: 10.6023/cjoc202109048

Abstract

Two new shikimic acid-derived trachshikimics A and B, together with four known biogenetically related shikimic acid derivatives, were isolated from the flower of Trachycarpus fortunei (Hook.) H. Wendl. Their structures were elucidated using comprehensive spectroscopic methods and chemical reaction. All isolated compounds showed α-glucosidase inhibitory activities, while Trachshikimic B (2), 3-feruloylquinic acid (5) and chlorogenic acid (6) were more active than the positive control acarbose.

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