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2022 , Vol. 42 >Issue 2: 619 - 630

DOI: https://doi.org/10.6023/cjoc202108026

研究论文

吲唑吡啶喹啉铱负载催化剂的合成及在2-氨基苯并噻唑N-烷基化反应中的应用

  • 李家豪 ,
  • 刘洪强 ,
  • 张博 ,
  • 葛冰洋 ,
  • 王大伟
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  • a 江南大学化学与材料工程学院 教育部合成与生物胶体重点实验室 江苏无锡 214122
    b 蚌埠中实化学技术有限公司 安徽蚌埠 233000

收稿日期: 2021-08-17

  修回日期: 2021-09-08

  网络出版日期: 2022-02-24

基金资助

国家自然科学基金(21776111)

收起

Synthesis of Supported Indazolyl-Pyridyl-Quinoline Iridium Catalyst and Its Application to N-Alkylation of 2-Aminobenzothiazoles

  • Jiahao Li ,
  • Hongqiang Liu ,
  • Bo Zhang ,
  • Bingyang Ge ,
  • Dawei Wang
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  • a Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu 214122
    b China Synchem Technology Co., Ltd., Bengbu, Anhui 233000
* Corresponding author. E-mail:

Received date: 2021-08-17

  Revised date: 2021-09-08

  Online published: 2022-02-24

Supported by

National Natural Science Foundation of China(21776111)

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摘要

设计合成了一种多氮唑类三齿配体, 并将其与铱配合物成功负载至MoS2纳米片上, 制备出了非均相催化剂IPQ-Ir@MoS2. 利用扫描电子显微镜(SEM)、透射电子显微镜(TEM)、X射线能谱仪(EDS)、X射线光电能谱(XPS), 对该催化剂进行表征与分析. 该催化剂能够实现2-氨基苯并噻唑与苯甲醇的无溶剂N-烷基化反应, 在反应中表现出优异的催化活性和良好的底物普适性, 对反应机理进行了探索.

关键词： 借氢; 脱氢; 三齿配体; 铱; 负载型催化剂

本文引用格式

李家豪 , 刘洪强 , 张博 , 葛冰洋 , 王大伟 . 吲唑吡啶喹啉铱负载催化剂的合成及在2-氨基苯并噻唑N-烷基化反应中的应用[J]. 有机化学, 2022 , 42(2) : 619 -630 . DOI: 10.6023/cjoc202108026

Abstract

The tridentate indazolyl-pyridyl-quinoline ligand was designed and synthesized, and its iridium complex was successfully loaded on MoS2 nanosheets. The resulting IPQ-Ir@MoS2 was fully characterized by means of scanning electron microscope (SEM), transmission electron microscopy (TEM), energy dispersive spectrometer (EDS) and X-ray photoelectron spectrometry (XPS). This iridium composite could realize N-alkylation of 2-aminobenzothiazole with benzyl alcohol under solvent-free condition. It showed excellent catalytic activity and good tolerance. At the same time, the reaction mechanism was also explored.

Key words： borrowing hydrogen; dehydrogenation; tridentate ligand; iridium; supported catalyst

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