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2022 , Vol. 42 >Issue 8: 2300 - 2321

DOI: https://doi.org/10.6023/cjoc202203007

综述与进展

α-羟基酮类化合物参与的反应研究进展

  • 王君姣 ,
  • 吕瑜瑜 ,
  • 尚永伟 ,
  • 崔振丽 ,
  • 王克虎 ,
  • 黄丹凤 ,
  • 胡雨来
展开
  • 西北师范大学化学学工学院 兰州 730050
† 共同第一作者

收稿日期: 2022-03-01

  修回日期: 2022-04-07

  网络出版日期: 2022-05-18

基金资助

甘肃省自然科学基金(18JR3RA091); 甘肃省自然科学基金(21JR7RA136)

收起

Research Progress of Reactions Participated by α-Hydroxy Ketones

  • Junjiao Wang ,
  • Yuyu Lv ,
  • Yongwei Shang ,
  • Zhenli Cui ,
  • Ke-Hu Wang ,
  • Danfeng Huang ,
  • Yulai Hu
Expand
  • College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070
† These authors contributed equally to this work.
* E-mail:

Received date: 2022-03-01

  Revised date: 2022-04-07

  Online published: 2022-05-18

Supported by

Natural Science Foundation of Gansu Province(18JR3RA091); Natural Science Foundation of Gansu Province(21JR7RA136)

Fold

摘要

α-羟基酮是一类非常重要的化合物, 不仅是许多具有生物活性的天然产物的重要结构片段, 而且作为重要的合成砌块被应用于多种具有生物活性的化合物及药物的合成中. 整理和总结了α-羟基酮类化合物参与的亲核加成反应以及环加成反应.

关键词： α-羟基酮; 亲核加成反应; 环加成反应

本文引用格式

王君姣 , 吕瑜瑜 , 尚永伟 , 崔振丽 , 王克虎 , 黄丹凤 , 胡雨来 . α-羟基酮类化合物参与的反应研究进展[J]. 有机化学, 2022 , 42(8) : 2300 -2321 . DOI: 10.6023/cjoc202203007

Abstract

α-Hydroxyl ketones are an important class of compounds. They are not only the key structural fragments of many biologically active natural products, but also the important synthetic building blocks, hence α-hydroxyl ketones are employed in the synthesis of various biologically active molecules and drugs. The nucleophilic addition reactions and the cycloaddition reactions involving α-hydroxyl ketones are sorted out and summarized.

Key words： α-hydroxyl ketone; nucleophilic addition reaction; cycloaddition reaction

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