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2025 , Vol. 45 >Issue 2: 707 - 716

DOI: https://doi.org/10.6023/cjoc202404002

研究论文

钯催化不对称碳氢键活化合成平面手性二茂铁磺酰胺化合物

  • 张朝威 ,
  • 徐兵斌 ,
  • 刘文龙 ,
  • 赵敬 ,
  • 段伟良
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  • a 扬州大学化学化工学院 江苏扬州 225002
    b 内蒙古大学化工学院 呼和浩特 010000

收稿日期: 2024-04-01

  修回日期: 2024-06-07

  网络出版日期: 2024-07-02

基金资助

国家自然科学基金(22371150); 江苏省研究生科研与实践创新计划(KYCX22-3457); 江苏省研究生科研与实践创新计划(YKYCX19-063)

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Palladium-Catalyzed Asymmetric C—H Activation for the Synthesis of Planar Chiral Ferrocene Sulfonamides

  • Chaowei Zhang ,
  • Bingbin Xu ,
  • Wenlong Liu ,
  • Jing Zhao ,
  • Weiliang Duan
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  • a College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002
    b College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010000
*E-mail:

Received date: 2024-04-01

  Revised date: 2024-06-07

  Online published: 2024-07-02

Supported by

National Natural Science Foundation of China(22371150); Postgraduate Research & Practice Innovation Program of Jiangsu Province(KYCX22-3457); Postgraduate Research & Practice Innovation Program of Jiangsu Province(YKYCX19-063)

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摘要

研究了钯催化下N-(2-溴芳基)-N-烷基二茂铁磺酰胺分子内不对称C—H键芳基化反应, 以优异的收率和最高90%的ee值合成了一系列新型的平面手性二茂铁磺酰胺化合物.

关键词： 钯催化; 平面手性; 二茂铁; 磺酰胺; C—H键活化

本文引用格式

张朝威 , 徐兵斌 , 刘文龙 , 赵敬 , 段伟良 . 钯催化不对称碳氢键活化合成平面手性二茂铁磺酰胺化合物[J]. 有机化学, 2025 , 45(2) : 707 -716 . DOI: 10.6023/cjoc202404002

Abstract

Pd-catalyzed asymmetric synthesis of planar chiral ferrocenes by enantioselective intramolecular C—H arylation of N-(2-bromoaryl)-N-alkylferrocenesulfonamide were efficiently achieved in good enantioselectivities (up to 90% ee) and high yields.

Key words： palladium catalysis; plane chirality; ferrocene; sulfonamide; C—H bond activation

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