叔磷及其氧化物与草酰溴反应生成相应的季鏻盐, 其作为活性中间体进一步转化可以实现醇的溴化、不饱和烃的双溴化等, 在有机合成中具有重要的研究价值. 设计合成了两种分子内均含有炔基的三芳基磷氧化物和苄基二芳基磷氧化物, 它们与草酰溴反应分别生成了新型的苯并磷杂环戊二烯季鏻三溴盐和E型磷酰化的二溴烯烃, 该结果与它们和草酰氯的反应结果均不相同. 另外, 制备得到的苯并磷杂环戊二烯季鏻三溴盐可作为溴素的替代试剂实现对芳烃、炔烃、烯烃以及苯乙酮等衍生物的直接溴化.

Tertiary phosphines and their oxides react with oxalyl bromide to generate corresponding quaternary phosphonium salts, which can be further transformed as active intermediates to facilitate the bromination of alcohols and the dibromination of unsaturated hydrocarbons. This chemical process carries substantial research significance in the field of organic synthesis. In this study, two types of triaryl phosphine oxides and benzyl diaryl phosphine oxides containing alkyne groups were designed and synthesized. These compounds were then subjected to reaction with oxalyl bromide, resulting in the formation of novel benzophosphonium tribromides and trans-phosphoryl dibromoalkenes, respectively. These findings demonstrate variations from their reactions with oxalyl chloride. Furthermore, the benzophosphonium tribromide obtained can act as an alternative reagent for bromine, enabling the direct bromination of aromatics compounds, olefin, alkyne and acetophenone derivatives.