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DOI: https://doi.org/10.6023/cjoc202507027

综述与进展

咪唑类化合物的合成研究进展

  • 赵咪娜 ,
  • 唐嘉一
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  • 陕西学前师范学院 生物食品与化学学院 陕西西安 710100

收稿日期: 2025-07-20

  修回日期: 2025-09-01

  网络出版日期: 2025-10-15

基金资助

国家自然科学基金项目(22201012)、陕西省创新能力支撑计划—青年科技新星项目(2024ZC-KJXX-039)和陕西高校优秀青年人才支持计划（2025QJ-02(内)）资助

收起

Progress in the synthesis of imidazole compounds

  • Zhao Mi-Na ,
  • Tang Jia-Yi
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  • School of Biological Food and Chemistry, Shaanxi Xueqian Normal University, Xi'an Shanxi 710100, China

Received date: 2025-07-20

  Revised date: 2025-09-01

  Online published: 2025-10-15

Supported by

National Natural Science Foundation of China (22201012)、the Innovation Capability Support Program of Shaanxi-Young Science and Technology Star Project (2024ZC-KJXX-039) and the Support Program for Outstanding Young Talents in Shaanxi Universities (2025QJ-02(inside)).

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摘要

咪唑类化合物是一类具有重要结构骨架的物质,其不仅是生物体内组氨酸的组分,也是核糖核酸和脱氧核糖核酸嘌呤的组分。同时,咪唑本身具有特殊的“酸碱两性”芳杂环结构和良好的电子转移性,因此其广泛的被应用在医药领域以及材料领域。本文结合近五年来国内外的研究报道,按照催化剂的类型对常见的合成策略进行了归纳总结,并对该领域未来发展趋势进行了展望。

关键词： 咪唑; 合成; 催化剂; 机理

本文引用格式

赵咪娜 , 唐嘉一 . 咪唑类化合物的合成研究进展[J]. 有机化学, 0 : 251018 . DOI: 10.6023/cjoc202507027

Abstract

Imidazole compounds are a class of substances with important structural skeletons, which are not only the components of histidine, but also the components of ribonucleic acid and purine of DNA. Imidazole itself has a special "acid-base amphoteric" aromatic heterocycle structure and good electron transfer ability, so it is widely used in the fields of medicine and materials. Based on the research reports in the past five years, the common synthesis strategies were summarized according to the types of catalysts, and the future development trend of this field was prospected.

Key words： imidazole; synthesis; catalyst; mechanism

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