Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (05): 815-824.DOI: 10.6023/cjoc1202021 Previous Articles     Next Articles




  1. a 中国科学院上海有机化学研究所有机氟化学重点实验室,上海200032;
    b 东华大学化学化工与生物工程学院,上海201620
  • 收稿日期:2012-02-02 修回日期:2012-03-01 发布日期:2012-04-10
  • 通讯作者: 卿凤翎
  • 基金资助:

    国家自然科学基金(Nos. 21072028, 20832008)和国家重点基础研究发展计划(No. 2012CB21600)资助项目.

Recent Advances of Trifluoromethylation

Qing Feng-Linga   

  1. a Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032;
    b College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620
  • Received:2012-02-02 Revised:2012-03-01 Published:2012-04-10
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21072028, 20832008) and the National Basic Research Program of China (No. 2012CB21600).

Many biologically active compounds contain the CF3 groups as the essential motif. As a result, much attention has been paid to the development of new synthetic methods for the introduction of the CF3 groups into diverse organic compounds. This review takes a critical look at recent advances of trifluoromethyltion reactions.

Key words: trifluoromethylation, organofluorine chemistry, advance