Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (6): 1571-1576.DOI: 10.6023/cjoc201611018 Previous Articles     Next Articles

Notes

β-酮酯和亚磷酸酯快速、实用和有效地合成烯醇酯

黄玲, 朱正, 曹天华, 雷学影, 龚久涵, 郭生梅, 蔡琥   

  1. 南昌大学化学学院 南昌 330031
  • 收稿日期:2016-11-16 修回日期:2017-01-12 发布日期:2017-01-20
  • 通讯作者: 蔡琥,郭生梅 E-mail:caihu@ncu.edu.cn
  • 基金资助:

    国家重点基础研究发展规划(973计划,No.2012CBA01204)和国家自然科学基金(No.21302084)资助项目.

Rapid, Practical and Efficient Synthesis of Enol Phosphates from β-Keto Esters and Phosphites

Huang Ling, Zhu Zheng, Cao Tianhua, Lei Xueying, Gong Jiuhan, Guo Shengmei, Cai Hu   

  1. College of Chemistry, Nanchang University, Nanchang 330031
  • Received:2016-11-16 Revised:2017-01-12 Published:2017-01-20
  • Contact: 10.6023/cjoc201611018 E-mail:caihu@ncu.edu.cn
  • Supported by:

    Project supported by the National Key Basic Research Program of China (973 Program, No. 2012CBA01204) and the National Natural Science Foundation of China (No. 21302084).

A useful strategy for the synthesis of enol phosphates from β-keto esters via Atherton-Atodd reaction was developed. A variety of enol phosphates can be quickly and readily prepared with broad substrate scope and moderate yields under mild conditions. This method provides a low cost and practical way to synthesize enol phosphates from β-keto esters.

Key words: enol phosphate, β-keto ester, Atherton-Todd reaction