Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (2): 304-315.DOI: 10.6023/cjoc201707002 Previous Articles     Next Articles



李闪闪, 洪海龙, 韩利民, 张田苗, 王云龙, 竺宁   

  1. 内蒙古工业大学化工学院 呼和浩特 010051
  • 收稿日期:2017-07-03 修回日期:2017-09-23 发布日期:2017-10-20
  • 通讯作者: 洪海龙, 竺宁;
  • 基金资助:


Research Progress for the Thiolysis Reaction of Halobenzonitrile

Li Shanshan, Hong Hailong, Han Limin, Zhang Tianmiao, Wang Yunlong, Zhu Ning   

  1. Chemical Engineering College, Inner Mongolia University of Technology, Hohhot 010051
  • Received:2017-07-03 Revised:2017-09-23 Published:2017-10-20
  • Contact: 10.6023/cjoc201707002;
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21362019), the Natural Science Foundation of Inner Mongolia (No. 2016MS0207) and the "Light of West China" Program of Chinese Academy of Sciences.

Halobenzonitrile is an important raw material in the fields of medicine, pesticide and materials. Halobenzonitrile has a nitrile group and a halo group which all could react with nucleophile reagents. The law for the selective synthesis of halothiobenzamide or mercaptobenzonitrile from the reaction of halobenzonitrile and different sulfur source is summarized. It is found that the halothiobenzamide product could be synthesized under protonic acid condition from halobenzonitrile, while the mercaptobenzonitrile product would be formed under the alkaline conditions.

Key words: chalcogens, heteroatom compounds, synthetic methods, halobenzonitrile, halothiobenzamide, mercaptobenzonitrile