Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (4): 752-759.DOI: 10.6023/cjoc201710001 Previous Articles     Next Articles



黄依铃, 包雯慧, 朱文明, 魏文廷   

  1. 宁波大学材料科学与化学工程学院 宁波 315211
  • 收稿日期:2017-10-06 修回日期:2017-11-16 发布日期:2017-12-05
  • 通讯作者: 魏文廷
  • 基金资助:


Recent Advances in Tetrabutylammonium Iodide/t-BuOOH Promoted C—N Bond Formation

Huang Yiling, Bao Wenhui, Zhu Wenming, Wei Wenting   

  1. School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211
  • Received:2017-10-06 Revised:2017-11-16 Published:2017-12-05
  • Contact: 10.6023/cjoc201710001
  • Supported by:

    Project supported by the Natural Science Foundation of Zhejiang Province (No. LQ18B020002) and the K. C. Wong Magna Fund in Ningbo University.

The construction of C-N bond is the foundation of organic synthesis, which plays a significant role in the synthesis of drug molecules, natural products and functional materials. Accordingly, it has been received much attention. Recently, the remarkable progress has been made in construction of C-N bond by using n-Bu4NI/t-BuOOH under transition-metal-free condition. Due to the relatively mild reaction condition and excellent selectivity, it provides an economy and efficient approach to construct C-N bond. In this review, the recent advances in this area are summarized on the basis of different nitrogen sources.

Key words: tetrabutylammonium iodide, tert-butyl hydroperoxide, C-N bond