Chin. J. Org. Chem. ›› 2018, Vol. 38 ›› Issue (3): 594-611.DOI: 10.6023/cjoc201710007 Previous Articles     Next Articles



松布尔, 李明辉, 穆赫塔尔·伊米尔艾山   

  1. 新疆大学化学与化工学院 乌鲁木齐 830046
  • 收稿日期:2017-10-09 修回日期:2017-10-19 发布日期:2017-11-03
  • 通讯作者: 穆赫塔尔·伊米尔艾山,
  • 基金资助:


Synthesis and Application of Acridine Derivatives

Songbuer, Li Minghui, Imerhasan Mukhtar   

  1. College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046
  • Received:2017-10-09 Revised:2017-10-19 Published:2017-11-03
  • Contact: 10.6023/cjoc201710007
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21462043).

Due to the special functional structural units and important applications in many fields, the study of acridine derivatives has become a hot topic worldwide. The large conjugated ring enables these dyes to be markers for fluorescence and imaging. Thanks to the ability of embedding into DNA chain, they have a wide range of applications in medicine and other fields. These dyes have the very similar color index value to that of the natural compounds. As an alternative to metal semiconductor material, acridines have presented potential value in the field of organic semiconductor materials. In recent years, emerging of the new and simple preparation technique, such as microwave assisted synthesis, metal free catalysis, one pot synthesis, and so on, has brought more attention to the synthesis and application of acridines. In this paper, various synthetic methods of acridine derivatives since 2010 and their applications in medicine, fluorescent materials, industrial dyeing materials and electroluminescence are introduced. The work about acridines accomplished in our group is also introduced. In the end, the future prospective of synthesis and application of acridine derivatives is proposed.

Key words: acridine derivative, synthetic method, three-component one-pot method, microwave