Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (5): 1088-1098.DOI: 10.6023/cjoc201702040 Previous Articles     Next Articles



董旭a,b, 侯永正a, 孟凡威a, 刘洪波a, 刘会a,b   

  1. a 湖南大学材料科学与工程学院 长沙 410082;
    b 山东理工大学化学与工程学院 淄博 255049
  • 收稿日期:2017-02-26 修回日期:2017-03-23 发布日期:2017-04-13
  • 通讯作者: 刘会
  • 基金资助:


Recent Advances on Alkyl-Heck Reaction

Dong Xua,b, Hou Yongzhenga, Meng Fanweia, Liu Hongboa, Liu Huia,b   

  1. a College of Materials Science and Engineering, Hunan University, Changsha 410082;
    b School of Chemical Engineering, Shandong University of Technology, Zibo 255049
  • Received:2017-02-26 Revised:2017-03-23 Published:2017-04-13
  • Contact: 10.6023/cjoc201702040
  • Supported by:

    Project supported by the China Postdoctoral Science Foundation (No. 2016M590736) and the Special Funding for Postdoctoral Innovation Project of Shandong Province (No. 201501002).

Recently, palladium-catalyzed alkyl-Heck reaction causes more attentions due to the wide application in the construction of C(sp3)-C(sp2). This review gives an up-to-date overview of alkyl-Heck reaction involving palladium radical intermediates, which are sorted in two categories of intramolecular reactions and intermolecular reactions. For most of these transformations, the plausible mechanisms are demonstrated in details. Clarification of these issues is the key point for understanding the palladium radical involved alkyl-Heck reactions and developing new high performance methodologies.

Key words: Pd-catalyzed, radical, Heck reaction, alkyl halide