Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (6): 1596-1612.DOI: 10.6023/cjoc201902001 Previous Articles     Next Articles

Special Issue: 金属有机化学 碳氢活化合辑2018-2019



施兆江, 王连会, 崔秀灵   

  1. 华侨大学生物医学学院 分子药物教育部工程研究中心 福建省分子医学重点实验室 厦门市海洋与基因药物重点实验室 厦门 361021
  • 收稿日期:2019-04-10 修回日期:2019-04-24 发布日期:2019-04-11
  • 通讯作者: 王连会, 崔秀灵;
  • 基金资助:


Recent Advances in the I2-Catalyzed C-H Bond Functionalizations

Shi Zhaojiang, Wang Lianhui, Cui Xiuling   

  1. Engineering Research Center of Molecular Medicine, Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021
  • Received:2019-04-10 Revised:2019-04-24 Published:2019-04-11
  • Contact: 10.6023/cjoc201902001;
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21602064, 21572072), the Science and Technology Project of Quanzhou City (No. 2018C073R), and the Postgraduates Innovative Fund in Scientific Research of Huaqiao University.

Heterocyclic compounds are widely applied in medicine, fine chemical engineering and the related industrial fields. Consequently, the development of efficient strategies for heterocycle constructions continues to be of great appeal in organic synthesis. In recent years, the I2-catalyzed direct C-H bond functionalizations have emerged as one of the most efficient synthetic protocols to construct diverse heterocycles. In this review, the recent advances in I2-catalyzed C-H bond functionalizations by the types of C-C and C-N/O/S bond formations are summarized, and an outlook of this research filed is given.

Key words: I2-catalysis, C-H bond activation, heterocycles