Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (6): 1588-1597.DOI: 10.6023/cjoc201911002 Previous Articles     Next Articles


刘幸a, 陶鹏b,d, 杨晶晶a, 刘雯a, 王华a, 王学宁c, 赵强d, 黄维扬b, 许并社a   

  1. a 太原理工大学 新材料界面科学与工程教育部重点实验室 山西太原 030024;
    b 香港理工大学应用生物与化学技术系 香港 999077;
    c 山西白求恩医院(山西医学科学院) 心脏大血管外科 山西太原 030032;
    d 南京邮电大学 有机电子与信息显示国家重点实验室培育基地 南京 210023
  • 收稿日期:2019-11-04 修回日期:2020-01-27 发布日期:2020-04-09
  • 通讯作者: 王华, 许并社;
  • 基金资助:

Hydrophilic Fluorescent Probes for Fe3+ Ions Based on Nanoparticles of Twisting D-π-A Type Compound Derived from Benzylidenemalononitrile

Liu Xinga, Tao Pengb,d, Yang Jingjinga, Liu Wena, Wang Huaa, Wang Xueningc, Zhao Qiangd, Wong Wai-yeungb, Xu Bingshea   

  1. a Key Laboratory of Interface Science and Engineering in Advanced Materials of Ministry of Education, Taiyuan University of Technology, Taiyuan, Shanxi 030024;
    b Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong 999077;
    c Department of Cardiovascular Surgery, Shanxi Baiqiuen Hospital(Shanxi Academy of Medical Sciences), Taiyuan, Shanxi 030032;
    d Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials, Nanjing University of Posts and Telecommunications(NUPT), Nanjing 210023
  • Received:2019-11-04 Revised:2020-01-27 Published:2020-04-09
  • Supported by:
    Project supported by the National Natural Scientific Foundation of China (Nos. 61775155, 61605138, 61705156, 61905120), the Shanxi Provincial Key Innovative Research Team in Science and Technology (No. 201601D021043), and the Hong Kong Polytechnic University (No. 1-ZE1C and 847S).

In this work, the novel fluorescent probes for detecting Fe3+ ions based on nanoparticles (TA-DF-BDM/PSMA NPs) of fluorescence material with twisting D-π-A configuration was designed and prepared, in which triphenylamine (TA), 9,9-dioctylfluorene (DF) and benzylidenemalononitrile (BDM) serve as electron donor (D) unit, π conjugated unit, and electron acceptor (A) unit, respectively. TA-DF-BDM/PSMA NPs exhibit red-emission peak located at 610 nm in photoluminescence spectrum and larger stokes shifts (ca. 203 nm). And, TA-DF-BDM/PSMA NPs exhibit high selectivity for detecting Fe3+ ions in pure water with high sensitivity and low detection limit of 0.9833 μmol/L. More importantly, TA-DF-BDM/PSMA NPs show such properties as good photophysical stability, reversibility, excellent biocompatibility and low cytotoxicity, which can be utilized in bioimaging investigations.

Key words: fluorescent probes, Fe3+ ions, hydrophilcity, reversibility