Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (11): 3658-3667.DOI: 10.6023/cjoc202205054 Previous Articles Next Articles
Special Issue: 有机氟化学虚拟合辑
ARTICLES
收稿日期:
2022-05-31
修回日期:
2022-07-14
发布日期:
2022-08-25
通讯作者:
肖铁波, 江玉波
基金资助:
Jiazhuang Wang, Liguo Teng, Shaoqi Xiong, Tiebo Xiao(), Yubo Jiang(
)
Received:
2022-05-31
Revised:
2022-07-14
Published:
2022-08-25
Contact:
Tiebo Xiao, Yubo Jiang
Supported by:
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Jiazhuang Wang, Liguo Teng, Shaoqi Xiong, Tiebo Xiao, Yubo Jiang. Rh-Catalyzed gem-Difluoroallylation of N-Tosylhydrazones[J]. Chinese Journal of Organic Chemistry, 2022, 42(11): 3658-3667.
Entry | Catalyst | Base | Solvent | Temperature/℃ | Yieldb/% |
---|---|---|---|---|---|
1 | [Rh(OAc)2]2 | Cs2CO3 | DCE | 100 | 30 |
2 | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 81 |
3 | [Rh(OPiv)2]2 | Cs2CO3 | DCE | 100 | 48 |
4c | Cu(MeCN)4PF6 | Cs2CO3 | DCE | 100 | 0 |
5c | AgSbF6 | Cs2CO3 | DCE | 100 | 20 |
6 | [Rh(esp)]2 | LiOtBu | DCE | 100 | 53 |
7 | [Rh(esp)]2 | NaOtBu | DCE | 100 | 51 |
8 | [Rh(esp)]2 | K2CO3 | DCE | 100 | 62 |
9 | [Rh(esp)]2 | K3PO4 | DCE | 100 | 36 |
10 | [Rh(esp)]2 | Cs2CO3 | MeCN | 100 | 0 |
11 | [Rh(esp)]2 | Cs2CO3 | Dioxane | 100 | 75 |
12 | [Rh(esp)]2 | Cs2CO3 | THF | 100 | 69 |
13 | [Rh(esp)]2 | Cs2CO3 | DCE | 90 | 70 |
14 | [Rh(esp)]2 | Cs2CO3 | DCE | 110 | 80 |
15 | [Rh(esp)]2 | Cs2CO3 | DCE | 120 | 49 |
16d | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 78 |
17e | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 72 |
18f | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 80 |
19g | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 76 |
Entry | Catalyst | Base | Solvent | Temperature/℃ | Yieldb/% |
---|---|---|---|---|---|
1 | [Rh(OAc)2]2 | Cs2CO3 | DCE | 100 | 30 |
2 | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 81 |
3 | [Rh(OPiv)2]2 | Cs2CO3 | DCE | 100 | 48 |
4c | Cu(MeCN)4PF6 | Cs2CO3 | DCE | 100 | 0 |
5c | AgSbF6 | Cs2CO3 | DCE | 100 | 20 |
6 | [Rh(esp)]2 | LiOtBu | DCE | 100 | 53 |
7 | [Rh(esp)]2 | NaOtBu | DCE | 100 | 51 |
8 | [Rh(esp)]2 | K2CO3 | DCE | 100 | 62 |
9 | [Rh(esp)]2 | K3PO4 | DCE | 100 | 36 |
10 | [Rh(esp)]2 | Cs2CO3 | MeCN | 100 | 0 |
11 | [Rh(esp)]2 | Cs2CO3 | Dioxane | 100 | 75 |
12 | [Rh(esp)]2 | Cs2CO3 | THF | 100 | 69 |
13 | [Rh(esp)]2 | Cs2CO3 | DCE | 90 | 70 |
14 | [Rh(esp)]2 | Cs2CO3 | DCE | 110 | 80 |
15 | [Rh(esp)]2 | Cs2CO3 | DCE | 120 | 49 |
16d | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 78 |
17e | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 72 |
18f | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 80 |
19g | [Rh(esp)]2 | Cs2CO3 | DCE | 100 | 76 |
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