Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (10): 3644-3651.DOI: 10.6023/cjoc202304029 Previous Articles     Next Articles

Special Issue: 有机硅化学专辑-2023

铜催化烯醇硅醚与芳基亚磺酸钠合成β-酮砜的研究

许力, 吕兰兰*(), 王香善*()   

  1. 江苏师范大学化学与材料科学学院 江苏徐州 221116
  • 收稿日期:2023-04-20 修回日期:2023-06-02 发布日期:2023-06-26
  • 基金资助:
    江苏省高校面上项目(22KJD150003); 2023年度江苏师范大学实验室研究课题(L2023YB08)

Copper-Catalyzed Synthesis of β-Keto Sulfones from Enol Silyl Ether and Sodium Arylsulfinates

Li Xu, Lanlan Lü(), Xiangshan Wang()   

  1. School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116
  • Received:2023-04-20 Revised:2023-06-02 Published:2023-06-26
  • Contact: *E-mails: lll800@126.com; xswang@jsnu.edu.cn
  • Supported by:
    Higher Education Program in Jiangsu Province(22KJD150003); FY2023 Jiangsu Normal University Laboratory Research Project(L2023YB08)

β-Keto sulfones are an important group of sulfur-containing compounds and intermediates for organic synthesis, which are widely used in the construction of natural products and various important organic compounds. A method for the rapid synthesis of β-keto sulfones catalyzed by copper bromide from enol silyl ether and sodium arylsulfinates is developed, which has the advantages of simple operation, mild conditions and short reaction time.

Key words: β-keto sulfone, copper catalysis, enol silyl ether, sodium arylsulfinate