Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (8): 2471-2480.DOI: 10.6023/cjoc202112034 Previous Articles     Next Articles



陈飞a, 陶晟b, 刘宁b,*(), 代斌a,b,*()   

  1. a 天津大学化工学院 天津 300072
    b 石河子大学化学化工学院 新疆兵团绿色化工过程重点实验室 新疆石河子 832003
  • 收稿日期:2021-12-26 修回日期:2022-04-04 发布日期:2022-05-17
  • 通讯作者: 刘宁, 代斌
  • 基金资助:
    石河子市中青年科技创新领军人才计划(2019RC01); 石河子大学大型贵重仪器设备共享测试基金资助项目

CNN-Type Binuclear Cu(I) Complexes Catalyzed Direct Carboxylation via the Fixation of CO2 at Room Temperature

Fei Chena, Sheng Taob, Ning Liub(), Bin Daia,b()   

  1. a School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072
    b Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi, Xinjiang 832003
  • Received:2021-12-26 Revised:2022-04-04 Published:2022-05-17
  • Contact: Ning Liu, Bin Dai
  • Supported by:
    Young and Middle-Aged Leading Scientists Program of Shihezi City(2019RC01); Open Sharing Fund for the Large-scale Instruments and Equipment of Shihezi University.

A type of CNN-type binuclear Cu(Ⅰ) complexes was used in the direct carboxylation of the terminal alkynes under room temperature and atmospheric CO2 with a low catalyst loading. A broad range of the terminal alkynes were tolerated, leading to the desired propiolic acids in 83%~97% yields. The method was successfully applied to continuous carboxylation and esterification of hetero arenes. The control experimental results and literature suggest that Cs2CO3 promotes the removal of terminal alkyne hydrogen atoms, and Cu(Ⅰ) complexes play an important role in the activation of terminal alkyne by the interaction between Cu(I) center and alkynyl group.

Key words: carbon dioxide, terminal alkyne, copper catalysis, carboxylation, C—H activation