Chiral organoselenium compounds are widely found in bioactive molecules, natural products, pharmaceutical agents, and functional materials. They also serve as important intermediates and catalysts in organic synthesis. Given the significance of such compounds, the synthesis of chiral organoselenium compounds has long been a hot research topic in organic chemistry. In recent years, the development of environmentally benign and cost-effective methods for synthesizing chiral organoselenium compounds has attracted considerable attention. This article reviews the research progress in the synthesis of chiral organoselenium compounds under different catalytic systems over the past decade. This review is organized into three catalytic systems: metal-free catalysis, metal catalysis, and photocatalysis, and the research progress of each system is discussed in detail. Additionally, the challenges and future directions in the synthesis of chiral organoselenium compounds are also discussed.

Key words: Metal-free catalysis, metal-catalysis, photocatalysis, chiral organoselenium compounds