Chin. J. Org. Chem. ›› 1987, Vol. 7 ›› Issue (5): 354-356. Previous Articles     Next Articles

内分子DIELS-ALDER反应合成DRIMANE类倍半萜化合物DRIMENIN, POLYGODIAL及CINNAMOLIDE的全合成

贺菊芳;吴毓林   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1987-10-25

The intramolecular Diels-Alder approach to drimane related sesquiterpenes synthesis of drimenin, polygodial and cinnamolide

HE JUFONG;WU YULIN   

  • Published:1987-10-25

Drimane sesquiterpenes were prepared via an intramol. Diels-Alder reaction of b-ionone derivative I to by intermediate II. Reduction, lactonization, hydrogenation and dehydroxymethylation of II gave (?-drimenin (III; RR = O, R1 = H). (?-Polgodial (IV) and (?-cinnamolide (III; R = H, R1R1 = O) were then prepared from III (RR = O, R1 = H) via reduction and oxidation

Key words: LACTONES, FURANONE P, SESQUITERPENE, DECALIN P, NAPHTHALENECARBOXYLIC ACID P, DIELS-ALDER REACTION

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